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Merck

GW22921

Sigma-Aldrich

Anti-ST8SIA1 antibody produced in chicken

affinity isolated antibody, buffered aqueous solution

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About This Item

UNSPSC-Code:
12352203
NACRES:
NA.41

Biologische Quelle

chicken

Qualitätsniveau

Konjugat

unconjugated

Antikörperform

affinity isolated antibody

Antikörper-Produkttyp

primary antibodies

Klon

polyclonal

Form

buffered aqueous solution

Speziesreaktivität

human

Methode(n)

western blot: suitable

NCBI-Hinterlegungsnummer

UniProt-Hinterlegungsnummer

Versandbedingung

wet ice

Lagertemp.

−20°C

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

human ... ST8SIA1(6489)

Verwandte Kategorien

Allgemeine Beschreibung

The previously assigned protein identifier Q6PZN5 has been merged into Q92185. Full details can be found on the UniProt database.

Immunogen

Immunogen Sequence: GI # 4506953, sequence 4-18
Synthetic peptide sequence of ST8 α-N-acetyl-neuraminide α-2,8-sialyltransferase 1.

Anwendung

Anti-ST8SIA1 antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

Biochem./physiol. Wirkung

α-N-acetylneuraminide α-2,8-sialyltransferase is an enzyme encoded by the ST8SIA1 gene in humans. It acts as an oligosialyltransferase in a cellular context. ST8SIA1 gene encodes a ganglioside synthase and is susceptibile to diseases. The gene is found to be associated with Multiple sclerosis (MS).

Physikalische Form

Solution in phosphate buffered saline containing 0.02% sodium azide.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 1

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


Analysenzertifikate (COA)

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In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

Sreeram V Ramagopalan et al.
Journal of neuroimmunology, 212(1-2), 142-144 (2009-05-12)
Multiple sclerosis (MS) is a complex trait with a significant genetic component. Recent work has implicated the ST8SIA1 gene, encoding a ganglioside synthase, in susceptibility to the disease, perhaps with a parent-of-origin effect. In this investigation of 1318 MS patients
Agata Steenackers et al.
Molecules (Basel, Switzerland), 17(8), 9559-9572 (2012-08-14)
Glycosphingolipids from the ganglio-series are usually classified in four series according to the presence of 0 to 3 sialic acid residues linked to lactosylceramide. The transfer of sialic acid is catalyzed in the Golgi apparatus by specific sialyltransferases that show

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