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GW22768

Sigma-Aldrich

Anti-MAPK1 antibody produced in chicken

affinity isolated antibody, buffered aqueous solution

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About This Item

UNSPSC-Code:
12352203
NACRES:
NA.41

Biologische Quelle

chicken

Qualitätsniveau

200

Konjugat

unconjugated

Antikörperform

affinity isolated antibody

Antikörper-Produkttyp

primary antibodies

Klon

polyclonal

Form

buffered aqueous solution

Speziesreaktivität

rat, mouse, human

Hersteller/Markenname

Genway 15-288-22768

Methode(n)

western blot: suitable

NCBI-Hinterlegungsnummer

NP_620407.1

UniProt-Hinterlegungsnummer

P28482

Versandbedingung

wet ice

Lagertemp.

−20°C

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

human ... MAPK1(5594)

Immunogen

Immunogen Sequence: GI # 20986531, sequence 232-360
Recombinant mitogen-activated protein kinase 1

Anwendung

Anti-MAPK1 antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

Biochem./physiol. Wirkung

Mitogen-activated protein kinase 1 is an enzyme encoded by the MAPK1 gene in humans. RAS/mitogen - activated protein kinase (MAPK) pathway plays a crucial role in embryonic and postnatal development. It is also associated with COPD (chronic obstructive pulmonary disease) and p38 MAPK may have a a potential target for the treatment of COPD.

Physikalische Form

Solution in phosphate buffered saline containing 0.02% sodium azide.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 1

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Analysenzertifikate (COA)

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Natalia Bezniakow et al.
Developmental period medicine, 18(3), 285-296 (2014-09-04)
The RASopathies are a class of developmental syndromes. Each of them exhibits distinctive phenotypic features, although there are numerous overlapping clinical manifestations that include: dysmorphic craniofacial features, congenital cardiac defects, skin abnormalities, varying degrees of intellectual disability and increased risk
Cuiping Huang et al.
Medical science monitor : international medical journal of experimental and clinical research, 19, 1229-1235 (2014-01-03)
Inflammation and remodeling of the small airways are major determinants of the progression and severity of COPD. The present study explored the correlation between sputum p38 mitogen-activated protein kinase (MAPK) activity and airway inflammation and reduction of lung function in
Gwendolyn I Humphreys et al.
PloS one, 9(11), e111975-e111975 (2014-11-06)
17β-estradiol (E2) plays critical roles in a number of target tissues including the mammary gland, reproductive tract, bone, and brain. Although it is clear that E2 reduces inflammation and ischemia-induced damage in the cerebral cortex, the molecular mechanisms mediating the
Cynthia L Neben et al.
Human molecular genetics, 23(21), 5659-5671 (2014-06-09)
Fibroblast growth factor receptor 2 (FGFR2) promotes osteoprogenitor proliferation and differentiation during bone development, yet how the receptor elicits these distinct cellular responses remains unclear. Analysis of the FGFR2-skeletal disorder bent bone dysplasia syndrome (BBDS) demonstrates that FGFR2, in addition
Ji-Hee Kim et al.
Oncology reports, 31(6), 2708-2712 (2014-05-03)
Protein tyrosine kinase 7 (PTK7) is a catalytically inactive receptor tyrosine kinase that is also known as colon carcinoma kinase-4 (CCK-4). Recent reports have shown that PTK7 plays an important role in carcinogenesis, and it is known to be upregulated
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