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Merck

GW20070F

Sigma-Aldrich

Anti-APOB antibody produced in chicken

affinity isolated antibody, buffered aqueous solution

Synonym(e):

Anti-Apolipoprotein B, Anti-Apolipoprotein B-100

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About This Item

MDL-Nummer:
UNSPSC-Code:
12352203
NACRES:
NA.41

Biologische Quelle

chicken

Qualitätsniveau

Konjugat

unconjugated

Antikörperform

affinity isolated antibody

Antikörper-Produkttyp

primary antibodies

Klon

polyclonal

Form

buffered aqueous solution

Speziesreaktivität

human

Hersteller/Markenname

Genway 15-288-20070F

Methode(n)

indirect ELISA: suitable
western blot: suitable

NCBI-Hinterlegungsnummer

UniProt-Hinterlegungsnummer

Versandbedingung

wet ice

Lagertemp.

−20°C

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

human ... APOB(338)

Immunogen

Apolipoprotein B-100 native protein.
Immunogen Sequence: GI # 4502153, sequence 1-4563

Anwendung

Anti-APOB antibody produced in chicken is suitable for indirect ELISA and western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200. It may also be used for serum lipid analyses and apolipoprotein assays.

Biochem./physiol. Wirkung

Apolipoprotein B (apoB) is the main protein component of triacylglyceride (TAG)-rich lipoproteins. It includes chylomicrons as well as very low density lipoprotein (the "bad cholesterol"). The N-terminal domains of apoB support the intrinsic capability of co-translational lipid recruitment. Apolipoprotein B is considered as a key structural component of all the atherogenic lipoproteins and its genetic variation may affect plasma ApoB and lipid levels, which may influence atherogenesis.

Physikalische Form

Solution in phosphate buffered saline containing 0.02% sodium azide.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 1

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


Analysenzertifikate (COA)

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Jovana Nikolajevic Starcevic et al.
VASA. Zeitschrift fur Gefasskrankheiten, 43(3), 171-180 (2014-05-07)
Apolipoprotein B is a key structural component of all the atherogenic lipoproteins (LDL, VLDL and IDL). Genetic variations of the ApoB gene may affect plasma ApoB and lipid levels, thus influencing atherogenesis. The present study was designed to investigate the
A A Qureshi et al.
The Journal of nutrition, 131(2), 223-230 (2001-02-13)
A tocotrienol-rich fraction (TRF(25)) and novel tocotrienols (d-P(21)-T3 and d-P(25)-T3) of rice bran significantly lowered serum and low density lipoprotein cholesterol levels in chickens. The present study evaluated the effects of novel tocotrienols on lipid metabolism in swine expressing hereditary
Matthew A Mitsche et al.
The Journal of biological chemistry, 289(13), 9000-9012 (2014-02-12)
Apolipoprotein B (apoB) is the principal protein component of triacylglyceride (TAG)-rich lipoproteins, including chylomicrons and very low density lipoprotein, which is the precursor to LDL (the "bad cholesterol"). TAG-rich lipoprotein assembly is initiated by the N-terminal βα1 superdomain of apoB
M B Elam et al.
Arteriosclerosis, thrombosis, and vascular biology, 18(12), 1942-1947 (1998-12-16)
Cilostazol is an antiplatelet agent and vasodilator marketed in Japan for treatment of ischemic symptoms of peripheral vascular disease. It is currently being evaluated in the United States for treatment of symptomatic intermittent claudication (IC). Cilostazol has been shown to

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