G8293

Galanin (2-11) porcine, rat

≥97% (HPLC), lyophilized powder

• Empirische Formel (Hill-System): C₅₄H₈₁N₁₃O₁₄
• Molekulargewicht: 1136.30
• MDL-Nummer: MFCD05664726
• UNSPSC-Code: 12352209
• PubChem Substanz-ID: 329799978
• NACRES: NA.32

Eigenschaften

• Biologische Quelle: synthetic
• Qualitätsniveau: 200
• Assay: ≥97% (HPLC)
• Form: lyophilized powder
• Zusammensetzung: Peptide content, ≥65%
• UniProt-Hinterlegungsnummer: P10683
• Lagertemp.: −20°C
• SMILES String: CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc2c[nH]c3ccccc23)[C@@H](C)O)C(N)=O
• InChI: 1S/C54H81N13O14/c1-26(2)17-37(46(57)73)62-49(76)38(18-27(3)4)63-51(78)40(20-31-13-15-33(70)16-14-31)61-44(72)24-59-47(74)29(7)60-53(80)42(25-68)66-52(79)41(22-43(56)71)64-50(77)39(19-28(5)6)65-54(81)45(30(8)69)67-48(75)35(55)21-32-23-58-36-12-10-9-11-34(32)36/h9-16,23,26-30,35,37-42,45,58,68-70H,17-22,24-25,55H2,1-8H3,(H2,56,71)(H2,57,73)(H,59,74)(H,60,80)(H,61,72)(H,62,76)(H,63,78)(H,64,77)(H,65,81)(H,66,79)(H,67,75)/t29-,30+,35-,37-,38-,39-,40-,41-,42-,45-/m0/s1
• InChIKey: SUJPPMXJCZETOA-ZKEPBWIVSA-N
• Angaben zum Gen: rat ... Gal(29141)

Beschreibung

Amino Acid Sequence

Trp-Thr-Leu-Asn-Ser-Ala-Gly-Tyr-Leu-Leu-NH2

Allgemeine Beschreibung

Galanin (2-11) is a galanin receptor type 2 agonist.

Biochem./physiol. Wirkung

Studies in mice show that injection of galanin (2-11) has anticonvulsant activity in seizure affected animals with an intact DR (dorsal root)–hippocampal serotonergic profile, and has no effect in animals with absent 5-HT (hydroxytryptamine) profile.

Sonstige Hinweise

Lyophilized from 0.1% TFA in H2O

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)