G133

GR 89696 fumarate salt

solid

• Synonym(e): 4-[(3,4-Dichlorophenyl)acetyl]-3-(1-pyrrolidinylmethyl)-1-piperazinecarboxylic acid methyl ester fumarate salt
• Empirische Formel (Hill-System): C₁₉H₂₅Cl₂N₃O₃ · C₄H₄O₄
• CAS-Nummer: 126766-32-3
• Molekulargewicht: 530.40
• MDL-Nummer: MFCD00274044
• UNSPSC-Code: 12352200
• PubChem Substanz-ID: 24278038
• NACRES: NA.77

Eigenschaften

• Form: solid
• Qualitätsniveau: 100
• Farbe: off-white
• Löslichkeit: ethanol: 4.0 mg/mL; DMSO: >50 mg/mL; H₂O: 8.5 mg/mL
• SMILES String: OC(=O)\C=C\C(O)=O.COC(=O)N1CCN(C(CN2CCCC2)C1)C(=O)Cc3ccc(Cl)c(Cl)c3
• InChI: 1S/C19H25Cl2N3O3.C4H4O4/c1-27-19(26)23-8-9-24(15(13-23)12-22-6-2-3-7-22)18(25)11-14-4-5-16(20)17(21)10-14;5-3(6)1-2-4(7)8/h4-5,10,15H,2-3,6-9,11-13H2,1H3;1-2H,(H,5,6)(H,7,8)/b;2-1+
• InChIKey: ABTNETSDXZBJTE-WLHGVMLRSA-N
• Angaben zum Gen: human ... OPRK1(4986)

Beschreibung

Anwendung

GR 89696 fumarate salt has been used as a κ κ2 opioid receptor (KOR) agonist to study its anti-scratching and antipruritic effects on monkeys.

Biochem./physiol. Wirkung

GR 89696 fumarate is a selective κ2 opioid receptor agonist.

Rechtliche Hinweise

Sold for research purposes under agreement from Glaxo­Smith­Kline

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)