E5630
β-Estradiol 6-(O-carboxymethyl)oxime: BSA
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About This Item
Empfohlene Produkte
Sterilität
non-sterile
Qualitätsniveau
Form
lyophilized powder
Kennzeichnungsgrad
~30 mol steroid per mol BSA
Löslichkeit
phosphate buffer: 0.90-1.10 mg/mL, faintly hazy to hazy, colorless to faintly yellow
Versandbedingung
ambient
Lagertemp.
2-8°C
Allgemeine Beschreibung
β-Estradiol 6-(O-carboxymethyl)oxime: BSA is an estradiol conjugate and is membrane-impermeable. BSA is linked to the estradiol at position 6 to form the β-estradiol 6-(O-carboxymethyl) oxime: BSA conjugate.
Anwendung
β-Estradiol 6-(O-carboxymethyl)oxime: BSA has been used:
- to test its effect on the N-methyl-D-aspartate receptor (NMDAR) currents in female dorsal root ganglion (DRG) neurons
- to coat microplates for the detection of plasma 17β-Estradiol levels using indirect enzyme-linked immunosorbent assay (ELISA)
- to test its effect on MutL homolog 1 in colorectal cancer lines
Biochem./physiol. Wirkung
β-Estradiol 6-(O-carboxymethyl)oxime: BSA mimics estrogen and favors amyloid precursor protein α (sAPPα) secretion in vitro studies with primary rat cortical neurons. It also stimulates mitogen-activated protein kinase (MAPK) activity in human umbilical vein endothelial cells
Signalwort
Warning
H-Sätze
Gefahreneinstufungen
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 2
Lagerklassenschlüssel
11 - Combustible Solids
WGK
WGK 3
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
Persönliche Schutzausrüstung
Eyeshields, Gloves, type P3 (EN 143) respirator cartridges
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Journal of molecular neuroscience : MN, 61(3), 436-448 (2017-02-06)
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