D7408

2′,5′-Dideoxyadenosine

≥95% (HPLC), solid

• Synonym(e): 2ʹ,5ʹ-dd-Ado, NSC 95943
• Empirische Formel (Hill-System): C₁₀H₁₃N₅O₂
• CAS-Nummer: 6698-26-6
• Molekulargewicht: 235.24
• MDL-Nummer: MFCD00210904
• UNSPSC-Code: 41106305
• PubChem Substanz-ID: 24894132
• NACRES: NA.77

Eigenschaften

• Assay: ≥95% (HPLC)
• Form: solid
• Farbe: white
• Löslichkeit: DMSO: soluble
• Lagertemp.: −20°C
• SMILES String: C[C@H]1O[C@H](C[C@@H]1O)n2cnc3c(N)ncnc23
• InChI: 1S/C10H13N5O2/c1-5-6(16)2-7(17-5)15-4-14-8-9(11)12-3-13-10(8)15/h3-7,16H,2H2,1H3,(H2,11,12,13)/t5-,6+,7-/m1/s1
• InChIKey: FFHPXOJTVQDVMO-DSYKOEDSSA-N
• Angaben zum Gen: rat ... Adcy2(81636)

Beschreibung

Anwendung

2′,5′-Dideoxyadenosine has been used to elucidate the mechanism of diligustilide (DLG). It has also been used to inhibit adenylate cyclase (AC).

Biochem./physiol. Wirkung

Cell-permeable adenylyl cyclase inhibitor. IC₅₀ = 2.7 μM in detergent-dispersed rat brain preparations.

Leistungsmerkmale und Vorteile

This compound is a featured product for Cyclic Nucleotide research. Click here to discover more featured Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound is featured on the Adenylyl cyclases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Rekonstituierung

Store at −20 °C after reconstitution.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)