D3689

(S)-3,5-Dihydroxyphenylglycine hydrate

≥98% (HPLC), powder

• Synonym(e): S-DHPG
• Empirische Formel (Hill-System): C₈H₉NO₄ · xH₂O
• CAS-Nummer: 162870-29-3
• Molekulargewicht: 183.16 (anhydrous basis)
• MDL-Nummer: MFCD11044457
• UNSPSC-Code: 12352209
• PubChem Substanz-ID: 24278366
• NACRES: NA.77

Eigenschaften

• Assay: ≥98% (HPLC)
• Form: powder
• Lagerbedingungen: desiccated; protect from light
• Farbe: white
• Lagertemp.: −20°C
• SMILES String: O.N[C@H](C(O)=O)c1cc(O)cc(O)c1
• InChI: 1S/C8H9NO4.H2O/c9-7(8(12)13)4-1-5(10)3-6(11)2-4;/h1-3,7,10-11H,9H2,(H,12,13);1H2/t7-;/m0./s1
• InChIKey: QZEFIWWBQUKNFA-FJXQXJEOSA-N
• Angaben zum Gen: human ... GRM1(2911)

Beschreibung

Anwendung

(S)-3,5-Dihydroxyphenylglycine hydrate has been used:

• as mGluR1/5 agonist for metabotropic glutamate receptor 1 (mGluR1/5) activation in synaptoneurosomal preparations
• in ACSF for DHPG stimulation
• to inject into basolateral amygdala to study its effect on memory expression

Biochem./physiol. Wirkung

(S)-3,5-Dihydroxyphenylglycine hydrate is a group I metabotropic glutamate receptor agonist.

Leistungsmerkmale und Vorteile

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound is featured on the Glutamate Receptors (G Protein Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Vorsicht

air sensitive

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H315,H319,H335
• P-Sätze: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves