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C9140

Sigma-Aldrich

Convallatoxin

≥65%

Synonym(e):

3β,5α,14-Trihydroxy-19-oxo-5β,20(22)-cardenolide 3-(6-deoxy-α-L-mannopyranoside), Strophanthidin α-L-rhamnopyranoside

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About This Item

Empirische Formel (Hill-System):
C29H42O10
CAS-Nummer:
508-75-8
Molekulargewicht:
550.64
EG-Nummer:
208-086-3
MDL-Nummer:
MFCD00069477
UNSPSC-Code:
12352200
PubChem Substanz-ID:
24893136
NACRES:
NA.77

Form

powder

Konzentration

≥65%

SMILES String

C[C@@H]1O[C@@H](O[C@H]2CC[C@]3(C=O)[C@H]4CC[C@]5(C)[C@H](CC[C@]5(O)[C@@H]4CC[C@]3(O)C2)C6=CC(=O)OC6)[C@H](O)[C@H](O)[C@H]1O

InChI

1S/C29H42O10/c1-15-22(32)23(33)24(34)25(38-15)39-17-3-8-27(14-30)19-4-7-26(2)18(16-11-21(31)37-13-16)6-10-29(26,36)20(19)5-9-28(27,35)12-17/h11,14-15,17-20,22-25,32-36H,3-10,12-13H2,1-2H3/t15-,17-,18+,19-,20+,22-,23+,24+,25-,26+,27-,28-,29-/m0/s1

InChIKey

HULMNSIAKWANQO-JQKSAQOKSA-N

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Biochem./physiol. Wirkung

A cardiac glycoside found in lily-of-the-valley with digitalis-like cardiac effects.

Piktogramme

Skull and crossbones
GHS06

Signalwort

Danger

Gefahreneinstufungen

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral

Lagerklassenschlüssel

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 2

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)

Analysenzertifikate (COA)

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Ouabain Octahydrat ≥95% (HPLC), powder

Sigma-Aldrich

O3125

Ouabain Octahydrat

Lanatosid C ≥97% (TLC)

Sigma-Aldrich

L2261

Lanatosid C

3,5-Dinitrobenzoesäure 99%

Sigma-Aldrich

121258

3,5-Dinitrobenzoesäure

[Prevention of frequent paroxysmal ventricular tachycardia by combined use of anti-arrhythmia drugs].
D F Kesler
Klinicheskaia meditsina, 59(11), 98-99 (1981-11-01)
B M Anner et al.
The American journal of physiology, 262(5 Pt 2), F843-F848 (1992-05-01)
The investigation of active Na-K transport inhibition by mercury is difficult to perform in a cell because of the presence of numerous other membrane and intracellular proteins modifiable by mercury. Thus purified Na-K-adenosinetriphosphatase (ATPase) molecules performing active transport in an
T V Amvros'eva et al.
Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 37(11), 5-8 (1992-11-01)
Currently used cardiovascular drugs such as nicotinamide, strophanthin, corglycon, curantyl, cavinton, papaverin hydrochloride, nicotinic acid, xantinole nicotinate, isoptin, parmidin and halidor were studied by the program of antiviral drug screening. The majority of them (9 out of 11) were shown
Amitava Dasgupta et al.
Journal of clinical laboratory analysis, 32(8), e22583-e22583 (2018-06-02)
Lily of the valley is a poisonous plant due to the presence of the cardiac glycoside convallatoxin which is known to interfere with serum digoxin measurement using the LOCI digoxin assay and other digoxin assays. We evaluated potential interference of
S B Frantsuzova et al.
Farmakologiia i toksikologiia, 43(6), 674-679 (1980-11-01)
The effect of convallotoxin on hemodynamics of the right and left ventricles and pressure in the pulmonary artery was studied in intact dogs and in surgical stenosis of the pulmonary trunk. In intact anesthetized dogs, convallotoxin produced changes in hemodynamics
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