C7017

Cholinchlorid

≥99%

• Synonym(e): (2-Hydroxyethyl)trimethylammoniumchlorid
• Lineare Formel: (CH₃)₃N(Cl)CH₂CH₂OH
• CAS-Nummer: 67-48-1
• Molekulargewicht: 139.62
• Beilstein: 3563126
• EG-Nummer: 200-655-4
• MDL-Nummer: MFCD00011721
• UNSPSC-Code: 50501514
• PubChem Substanz-ID: 57654039
• NACRES: NA.25

Eigenschaften

• Biologische Quelle: synthetic
• Assay: ≥99%
• Form: powder
• Farbe: white
• mp (Schmelzpunkt): 302-305 °C (dec.) (lit.)
• Lipid-Typ: phospholipids
• SMILES String: [Cl-].C[N+](C)(C)CCO
• InChI: 1S/C5H14NO.ClH/c1-6(2,3)4-5-7;/h7H,4-5H2,1-3H3;1H/q+1;/p-1
• InChIKey: SGMZJAMFUVOLNK-UHFFFAOYSA-M

Beschreibung

Allgemeine Beschreibung

Choline is a constituent of sphingomyelin and lecithin. It is a precursor of acetylcholine. Choline plays a vital role in methyl group metabolism, carcinogenesis and lipid transport. Choline deficiency is associated with fatty liver. It maintains cell structural integrity and cell signalling. Choline is implicated in the synthesis of phospholipids. It acts as a potent biomarker for ischemic heart disease.

Anwendung

Choline chloride has been used:

• in choline release assay
• as an endogenous agonist of sigma-1 receptors (Sig-1Rs)
• as a standard to analyse interrelationships between methionine and choline metabolism

Biochem./physiol. Wirkung

Choline is an essential nutrient, commonly grouped with the B complex vitamins, that plays key roles in many biological processes.

Substrate

Cholin-Acetyltransferase-Substrat

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves