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B7188

Sigma-Aldrich

Blonanserin

≥98% (HPLC)

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About This Item

Empirische Formel (Hill-System):
C23H30FN3
CAS-Nummer:
132810-10-7
Molekulargewicht:
367.50
MDL-Nummer:
MFCD00893838
UNSPSC-Code:
12352200
PubChem Substanz-ID:
329773292
NACRES:
NA.77

Qualitätsniveau

100

Assay

≥98% (HPLC)

Form

powder

Farbe

white to off-white

Löslichkeit

DMSO: ≥10 mg/mL

Ersteller

Dainippon Sumitomo

Lagertemp.

room temp

SMILES String

CCN1CCN(CC1)c2cc(-c3ccc(F)cc3)c4CCCCCCc4n2

InChI

1S/C23H30FN3/c1-2-26-13-15-27(16-14-26)23-17-21(18-9-11-19(24)12-10-18)20-7-5-3-4-6-8-22(20)25-23/h9-12,17H,2-8,13-16H2,1H3

InChIKey

XVGOZDAJGBALKS-UHFFFAOYSA-N

Biochem./physiol. Wirkung

Blonanserin is a D2/5-HT2 receptor antagonist; atypical antipsychotic.

Leistungsmerkmale und Vorteile

This compound was developed by Dainippon Sumitomo. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Piktogramme

Exclamation mark
GHS07

Signalwort

Warning

H-Sätze

H302,H413

Gefahreneinstufungen

Acute Tox. 4 Oral - Aquatic Chronic 4

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 1

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Analysenzertifikate (COA)

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Die Dokumentenbibliothek aufrufen

Taro Kishi et al.
Journal of psychiatric research, 47(2), 149-154 (2012-11-08)
There is uncertainty about the efficacy and tolerability of blonanserin in schizophrenia. PubMed, the Cochrane Library databases, PsycINFO, and Google Scholar were searched up to September 2012. A systematic review and meta-analysis of individual patient data from randomized, controlled trials
Yu-Guan Wen et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 903, 46-52 (2012-07-24)
Blonanserin is a novel atypical antipsychotic with highly selective receptor antagonist activity to dopamine D₂ and 5-HT(2A). N-desethyl blonanserin (blonanserin C) is its major active metabolite in human plasma. Herein we report a new highly sensitive, selective, and rapid liquid
Tadashi Ogawa et al.
Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 26(10), 1099-1102 (2010-10-19)
A rapid and sensitive method for analysis of blonanserin in human plasma by ultra-performance liquid chromatography-tandem mass spectrometry is presented. After pretreatment of a plasma sample by solid-phase extraction, blonanserin was analyzed by the system with a C(18) column. This
Case of delirium complicated with pneumonia that improved with blonanserin administration.
Hidehiro Andoh et al.
Psychiatry and clinical neurosciences, 64(5), 588-589 (2010-10-07)
Neuroleptic malignant syndrome induced by blonanserin.
Keiko Ohoyama et al.
The Journal of neuropsychiatry and clinical neurosciences, 23(1), E13-E13 (2011-02-10)
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