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A7883

Sigma-Aldrich

5α-Androst-16-en-3α-ol

Synonym(e):

Androstenol, 16-(5α)Androsten-3α-ol, 3α-Hydroxy-5α-androst-16-ene

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About This Item

Empirische Formel (Hill-System):
C19H30O
CAS-Nummer:
Molekulargewicht:
274.44
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
12352200
PubChem Substanz-ID:
NACRES:
NA.77

Biologische Quelle

synthetic (organic)

Qualitätsniveau

Assay

≥98% (TLC)

Form

powder

Arzneimittelkontrolle

regulated under CDSA - not available from Sigma-Aldrich Canada

Methode(n)

GC/MS: suitable

mp (Schmelzpunkt)

140-141 °C (lit.)

Löslichkeit

ethanol: 19.60-20.40 mg/mL, clear, colorless

Versandbedingung

ambient

Lagertemp.

room temp

SMILES String

C[C@]12CC[C@H]3[C@@H](CC[C@H]4C[C@H](O)CC[C@]34C)[C@@H]1CC=C2

InChI

1S/C19H30O/c1-18-9-3-4-16(18)15-6-5-13-12-14(20)7-11-19(13,2)17(15)8-10-18/h3,9,13-17,20H,4-8,10-12H2,1-2H3/t13-,14+,15-,16-,17-,18-,19-/m0/s1

InChIKey

KRVXMNNRSSQZJP-PHFHYRSDSA-N

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Anwendung

5-α-androst-16-en-3-α-ol (androstenol) is an androgen believed to act as a pheromone. Androstenol has been used in a study to develop a combined gas chromatography/thermal conversion/isotope ratio mass spectrometry (GC/TC/IRMS) method for D/H ratio determination of endogenous urinary steroids.

Biochem./physiol. Wirkung

5alpha-androst-16-en-3alpha-ol (androstenol), is an androgen believed to act as a pheromone.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)


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Thomas Piper et al.
Rapid communications in mass spectrometry : RCM, 23(13), 1917-1926 (2009-05-23)
The development and application of a combined gas chromatography/thermal conversion/isotope ratio mass spectrometry (GC/TC/IRMS) method for D/H ratio determination of endogenous urinary steroids are presented. The key element in sample preparation was the consecutive cleanup with high-performance liquid chromatography of
Jeremy Vincent et al.
Acta crystallographica. Section F, Structural biology and crystallization communications, 61(Pt 1), 156-159 (2006-03-02)
The constitutive androstane receptor (CAR) is a member of the nuclear receptor superfamily. In contrast to classical nuclear receptors, which possess small-molecule ligand-inducible activity, CAR exhibits constitutive transcriptional activity in the apparent absence of ligand. CAR is among the most
E L Hurden et al.
The Journal of endocrinology, 103(2), 179-186 (1984-11-01)
Three mature Large White boars were anaesthetized and received [7(n)-3H]pregnenolone by continuous infusion into right and left spermatic arteries for up to 180 min. Spermatic venous blood flow was measured by separate timed collections of completely diverted outflow from each
J J Cowley et al.
The Journal of steroid biochemistry and molecular biology, 39(4B), 647-659 (1991-10-01)
Student volunteers (38 of each sex) were exposed unknowingly overnight to the vapour of pheromonally active substances and compared with controls. The substances were either 5 alpha-16-androsten-3 alpha-ol (androstenol, occurring in human underarm sweat, and known to be pheromonally active
[Synthesis of mammalian pheromone 5 alpha-androst-16-en-3-one and 5 alpha-Androst-16-en-3 alpha-ol].
G D Han et al.
Yao xue xue bao = Acta pharmaceutica Sinica, 17(9), 696-698 (1982-09-01)

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