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A3759

Sigma-Aldrich

p-Aminohippuric acid sodium salt

Synonym(e):

N-(p-Aminobenzoyl)glycine

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About This Item

Lineare Formel:
C9H9N2O3Na
CAS-Nummer:
94-16-6
Molekulargewicht:
216.17
EG-Nummer:
202-309-8
MDL-Nummer:
MFCD00044689
UNSPSC-Code:
12352106
PubChem Substanz-ID:
24890806
NACRES:
NA.26

Assay

≥98% (TLC)

Form

powder

Farbe

white to off-white

Anwendung(en)

cell analysis

SMILES String

[Na].Nc1ccc(cc1)C(=O)NCC(O)=O

InChI

1S/C9H10N2O3.Na.H/c10-7-3-1-6(2-4-7)9(14)11-5-8(12)13;;/h1-4H,5,10H2,(H,11,14)(H,12,13);;

InChIKey

IGACXVXMVJUFOL-UHFFFAOYSA-N

Biochem./physiol. Wirkung

Para-Aminohippuric acid (PAH), OAT-1 specific, is used to help differentiate and characterized organic anion transporter (OAT) isoforms.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)

Analysenzertifikate (COA)

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Harnsäure ≥99%, crystalline

Sigma-Aldrich

U2625

Harnsäure

Chiao-Shih Tseng et al.
Advances in pharmacological sciences, 2011, 204501-204501 (2011-07-09)
The characteristics of aristolochic acid nephropathy (AAN) are interstitial fibrosis and atrophy of the proximal tubules, but with no change in glomeruli. To investigate the effects of AA on renal functions and the pharmacokinetics (PKs) of p-aminohippuric acid (PAH) and
Chi Chun Wong et al.
Biochemical pharmacology, 81(7), 942-949 (2011-01-20)
Flavonoids are conjugated by phase II enzymes in humans to form glucuronidated and sulfated metabolites that are excreted in urine via the kidney. In this study, we examined the interaction between metabolites of quercetin and isoflavonoids found in vivo with
Nadiya Bakhiya et al.
Toxicology, 264(1-2), 74-79 (2009-08-01)
Aristolochic acid (AA), present in Aristolochia species, is the major causative agent in the development of severe renal failure and urothelial cancers in patients with AA nephropathy. It may also be a cause of Balkan endemic nephropathy. Epithelial cells of
M M Al-Bataineh et al.
Journal of veterinary pharmacology and therapeutics, 35(3), 209-215 (2011-06-01)
Mammary epithelial cells express a diversity of membrane transporters including members of organic cation and organic anion (OAT) transporter subfamilies. Four mammal OAT isoforms have been identified: OAT-1, OAT-2, OAT-3, and OAT-4. The pharmacological significance of OAT isoforms has been
Andrew A Udy et al.
Critical care (London, England), 18(6), 657-657 (2014-11-30)
The aim of this study was to explore changes in glomerular filtration (GFR) and renal tubular function in critically ill patients at risk of augmented renal clearance (ARC), using exogenous marker compounds. This prospective, observational pharmacokinetic (PK) study was performed
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