A3543

Anti-Human IgG (whole molecule)−Agarose antibody produced in goat

IgG fraction of antiserum, PBS suspension

• MDL-Nummer: MFCD00162452
• UNSPSC-Code: 12352203
• NACRES: NA.46

Eigenschaften

• Biologische Quelle: goat
• Qualitätsniveau: 200
• Konjugat: agarose conjugate
• Antikörperform: IgG fraction of antiserum
• Antikörper-Produkttyp: secondary antibodies
• Klon: polyclonal
• Form: PBS suspension
• Speziesreaktivität: human
• Kennzeichnungsgrad: ~2.4 mg Ab per mL
• Methode(n): immunoelectrophoresis: suitable
• Kapazität: 1 mg/mL binding capacity
• Lagertemp.: 2-8°C
• Posttranslationale Modifikation Target: unmodified

Beschreibung

Allgemeine Beschreibung

IgG antibody subtype is the most abundant serum immunoglobulins of the immune system. It is secreted by B cells and is found in blood and extracellular fluids and provides protection from infections caused by bacteria, fungi and viruses. Maternal IgG is transferred to fetus through the placenta that is vital for immune defence of the neonate against infections.

Spezifität

Anti-human IgG recognizes human IgG (whole molecules). Goat anti-human is purified by ion exchange chromatography and then covalently bound to agarose.

Immunogen

Pooled normal human serum

Anwendung

Anti-human IgG (whole molecule) is suitable for immunoelectrophoresis. Antibody depletion from normal human serum was carried out by treating diluted serum with 50 microl of agarose-linked goat anti-human IgG (A3543) for 90 minutes at 4 °.

Antibody depletion from normal human serum was carried out by treating diluted serum with 50 μl of agarose-linked goat anti-human IgG (A3543) for 90 minutes at 4 degrees.

Biochem./physiol. Wirkung

IgG stimulates the classical pathway of the complement system. It neutralizes virus particles and toxins. IgG plays a crucial role in antibody-dependent cell-mediated cytotoxicity (ADCC). IgG might be associated with allergy. It has the longest serum half life.. Maternal IgG is transferred to fetus through the placenta that is vital for immune defence of the neonate against infections.

Physikalische Form

Suspension in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: nwg
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable