A1640

Adenosine 5′-O-thiomonophosphate dilithium salt

≥98%

• Synonym(e): 5′-AMPS
• Empirische Formel (Hill-System): C₁₀H₁₂Li₂N₅O₆PS
• CAS-Nummer: 93839-85-1
• Molekulargewicht: 375.15
• MDL-Nummer: MFCD00042996
• UNSPSC-Code: 41106305
• PubChem Substanz-ID: 24890572
• NACRES: NA.51

Eigenschaften

• Qualitätsniveau: 200
• Assay: ≥98%
• Form: powder
• Lagertemp.: −20°C
• SMILES String: [Li+].[Li]SP([O-])(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n2cnc3c(N)ncnc23
• InChI: 1S/C10H14N5O6PS.2Li/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(21-10)1-20-22(18,19)23;;/h2-4,6-7,10,16-17H,1H2,(H2,11,12,13)(H2,18,19,23);;/q;2*+1/p-2/t4-,6-,7-,10-;;/m1../s1
• InChIKey: FZXPFDFAEUBVHA-IDIVVRGQSA-L

Beschreibung

Anwendung

Adenosine 5′′-O-thiomonophosphate (5′-AMPS) is a 5′-O-thiophosphate which along with adenosine 5′-O-(2-thiodiphosphate) and adenosine 5′-O-(3-thiotriphosphate) can act as inhibitors of phosphohydrolases. AMPS is a substrate for smooth muscle endothelial ecto-5′-nucleotidase. 5′APMS is a stimulator of 5-lipoxygenase activity of rat polymorphonuclear (PMN) leukocytes. Histidine triad nucleotide-binding protein 1 (HINT-1) phosphoramidase transforms nucleoside 5′-O-phosphorothioates such as 5′-AMPS to nucleoside 5′-O-phosphates.

Sicherheitshinweise

• Piktogramme: GHS08,GHS07
• Signalwort: Warning
• H-Sätze: H302,H371
• P-Sätze: P260 - P264 - P270 - P301 + P312 - P308 + P311 - P405
• Gefahreneinstufungen: Acute Tox. 4 Oral - STOT SE 2
• Zielorgane: Eyes,Central nervous system
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable