80198

Methoxatin Dinatriumsalz

≥97.0% (HPLC)

• Synonym(e): PQQ, Pyrrolo-chinolin-chinon Dinatriumsalz
• Empirische Formel (Hill-System): C₁₄H₄N₂Na₂O₈
• CAS-Nummer: 122628-50-6
• Molekulargewicht: 374.17
• MDL-Nummer: MFCD00151711
• UNSPSC-Code: 12352005
• PubChem Substanz-ID: 329768729
• NACRES: NA.79

Eigenschaften

• Biologische Quelle: fermentation/recombinant
• Qualitätsniveau: 100
• Assay: ≥97.0% (HPLC)
• Form: powder
• Farbe: red-brown to deep orange; red-brown to deep red-brown
• Lagertemp.: 2-8°C
• SMILES String: OC(=O)c1cc(nc2C(=O)C(=O)c3cc([nH]c3-c12)C(=O)O[Na])C(=O)O[Na]
• InChI: 1S/C14H6N2O8.2Na/c17-10-4-2-6(14(23)24)15-8(4)7-3(12(19)20)1-5(13(21)22)16-9(7)11(10)18;;/h1-2,15H,(H,19,20)(H,21,22)(H,23,24);;/q;2*+1/p-2
• InChIKey: UFVBOGYDCJNLPM-UHFFFAOYSA-L

Beschreibung

Allgemeine Beschreibung

Methoxatin/pyrroloquinoline quinone (PQQ) is mostly seen in plants, few bacteria and single cell eukaryotes, like yeast. It is mainly obtained from methylotrophic bacteria. PQQ may also present in the tissues of mammals.

Anwendung

• Safety assessment of a novel, dietary pyrroloquinoline quinone disodium salt (mnemoPQQ): This study investigates the safety profile of Methoxatin disodium salt, which has implications for its application in assay development for clinical and diagnostic purposes. Specifically, it addresses the compound′s use in dietary supplements and potential crossover into clinical assays where safety and toxicity are paramount (Shiojima et al., 2022).

Biochem./physiol. Wirkung

In bacteria, pyrroloquinoline quinone (PQQ) is used as a redox cycling cofactor. It acts as a cofactor (prosthetic group) for enzyme-catalyzed redox reactions of glucose and methanol dehydrogenase(s). PQQ is used in liposomes to establish a simple homogeneous assay for the detection of membrane permeabilization by antimicrobial peptides and synthetic copolymers. In bovine plasma amine oxidase, methoxatin may acts as the cofactor.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)