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Sigma-Aldrich

D(+)-2-Phosphoglycerinsäure Natriumsalz Hydrat

≥75% (calc. on dry substance, enzymatic)

Synonym(e):

D-Glycerat-2-phosphat Natriumsalz

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About This Item

Empirische Formel (Hill-System):
C3H7O7P · xNa+ · yH2O
CAS-Nummer:
83418-48-8
Molekulargewicht:
186.06 (anhydrous free acid basis)
UNSPSC-Code:
12352204
PubChem Substanz-ID:
329768458
NACRES:
NA.26
Assay:
≥75% (calc. on dry substance, enzymatic)
Form:
powder

Qualitätsniveau

100

Assay

≥75% (calc. on dry substance, enzymatic)

Form

powder

Verunreinigungen

≤1% Pi
≤35% water

Lagertemp.

−20°C

SMILES String

O=C(O)[C@@H](CO)OP(O)(O)=O.C.C

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Verwandte Kategorien

Biochem./physiol. Wirkung

The enzyme enolase is responsible for reversible conversion of 2-phosphoglycerate (2-PG) into phosphoenolpyruvate (PEP). Phosphoglycerate mutase causes reversible isomerization of 3-phosphoglycerate and 2-phosphoglycerate in glycolysis and gluconeogenesis.
Enantiomerically pure metabolite of glycolysis/gluconeogenesis and also substrate for a number of important enzymes in central metabolism like enolase and phosphoglycerate mutase.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)

Hier finden Sie alle aktuellen Versionen:

Analysenzertifikate (COA)

Lot/Batch Number
SLCC9330
BCBT9037
BCBS7125V
BCBP4022V

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Jin-Ha Lee et al.
FEMS microbiology letters, 259(2), 240-248 (2006-06-01)
Enolase on the surface of streptococci putatively facilitates pathogenic invasion of the host organisms. The related Leuconostoc mesenteroides 512FMCM is nonpathogenic, but it too has an extracellular enolase. Purified isolates of extracellular dextransucrase from cultures of L. mesenteroides contain minute
Molecular characterization of phosphoglycerate mutase in archaea.
van der Oost J, et al.
FEMS Microbiology Letters, 212, 111-120 (2002)
Shivangi Agarwal et al.
Biochimica et biophysica acta, 1784(7-8), 986-994 (2008-05-06)
alpha-enolase of Bacillus anthracis has recently been classified as an immunodominant antigen and a potent virulence factor determinant. alpha-enolase (2-phospho-d-glycerate hydrolase (EC 4.2.1.11), a key glycolytic metalloenzyme catalyzes the dehydration of d-(+)-2-phosphoglyceric acid to phosphoenolpyruvate. Interaction of surface bound alpha-enolase
E Zhang et al.
Biochemistry, 36(41), 12526-12534 (1997-11-05)
Enolase, a glycolytic enzyme that catalyzes the dehydration of 2-phospho-d-glycerate (PGA) to form phosphoenolpyruvate (PEP), is a homodimer in all eukaryotes and many prokaryotes. Here, we report the crystal structure of a complex between yeast enolase and an equilibrium mixture
T M Larsen et al.
Biochemistry, 35(14), 4349-4358 (1996-04-09)
The equilibrium mixture of yeast enolase with substrate, 2-phospho-D-glycerate (2-PGA), and product, phosphoenolpyruvate (P-enolpyruvate), has been crystallized from solutions of poly(ethylene glycol) (PEG) at pH 8.0. Crystals belong to the space group C2 and have unit cell dimensions a =
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Artikel

Aerobic Glycolysis and the Warburg Effect

We presents an article about the Warburg effect, and how it is the enhanced conversion of glucose to lactate observed in tumor cells, even in the presence of normal levels of oxygen. Otto Heinrich Warburg demonstrated in 1924 that cancer cells show an increased dependence on glycolysis to meet their energy needs, regardless of whether they were well-oxygenated or not.

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