422R-1

PHOX2B (EP312) Rabbit Monoclonal Primary Antibody

• Synonym(e): Paired-like Homeobox 2B
• UNSPSC-Code: 12352203

Eigenschaften

• Biologische Quelle: rabbit
• Qualitätsniveau: 100; 500
• Konjugat: unconjugated
• Antikörperform: culture supernatant
• Antikörper-Produkttyp: primary antibodies
• Klon: EP312, monoclonal
• Beschreibung: For In Vitro Diagnostic Use in Select Regions
• Form: buffered aqueous solution
• Speziesreaktivität: human
• Verpackung: vial of 0.1 mL concentrate (422R-14); vial of 0.1 mL concentrate Research Use Only (422R-14-RUO); vial of 0.5 mL concentrate (422R-15); vial of 1.0 mL concentrate (422R-16); vial of 1.0 mL concentrate Research Use Only (422R-16-RUO); vial of 1.0 mL pre-dilute Research Use Only (422R-17-RUO); vial of 1.0 mL pre-dilute ready-to-use (422R-17); vial of 7.0 mL pre-dilute ready-to-use (422R-18); vial of 7.0 mL pre-dilute ready-to-use Research Use Only (422R-18-RUO)
• Hersteller/Markenname: Cell Marque^™
• Methode(n): immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100 (concentrated)
• Isotyp: IgG
• Kontrolle: neuroblastoma
• Versandbedingung: wet ice
• Lagertemp.: 2-8°C
• Visualisierung: nuclear
• Angaben zum Gen: human ... PHOX2B(8929)

Beschreibung

Allgemeine Beschreibung

Paired-like homeobox 2B (PHOX2B) is a transcription factor located on chromosome 4p13 which is crucial to the formation of autonomic ganglia in the autonomic nervous system (ANS). PHOX2B gene is strictly expressed in neural crest derivatives committed to the noradrenergic phenotype. The PHOX2B gene encodes a paired-like homeo-domain transcription factor with an extra-axial expression pattern restricted to the ANS. Neuroblasts of peripheral neuroblastic tumors are derived from the sympathoadrenal lineage, a division of the ANS. PHOX2B has been observed in peripheral neuroblastic tumors, neuroblastomas, paragangliomas, ganglioneuroblastomas, ganglioneuromas and pheochromocytomas. PHOX2B has been reported to be negative in other small round blue cell tumors.

Qualität

IVD

IVD

IVD

RUO

Verlinkung

PHOX2B Positive Control Slides, Product No. 422S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Physikalische Form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

Angaben zur Herstellung

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Sonstige Hinweise

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Rechtliche Hinweise

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

Sicherheitshinweise

• Lagerklassenschlüssel: 12 - Non Combustible Liquids
• WGK: WGK 2
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable