396M-1

Parvalbumin (2E11) Mouse Monoclonal Antibody

• UNSPSC-Code: 12352202
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: mouse
• Konjugat: unconjugated
• Antikörperform: culture supernatant
• Antikörper-Produkttyp: primary antibodies
• Klon: 2E11, monoclonal
• Beschreibung: For In Vitro Diagnostic Use in Select Regions (See Chart)
• Form: buffered aqueous solution
• Speziesreaktivität: human
• Verpackung: vial of 0.1 mL concentrate (396M-14); vial of 0.5 mL concentrate (396M-15); bottle of 1.0 mL predilute (396M-17); vial of 1.0 mL concentrate (396M-16); bottle of 7.0 mL predilute (396M-18)
• Hersteller/Markenname: Cell Marque^™
• Methode(n): immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:10-1:50
• Isotyp: IgG1
• Kontrolle: chromophobe renal cell carcinoma
• Versandbedingung: wet ice
• Lagertemp.: 2-8°C
• Visualisierung: cytoplasmic
• Angaben zum Gen: human ... PVALB(5816)

Beschreibung

Allgemeine Beschreibung

Parvalbumin is a calcium-binding protein that regulates cytosolic calcium homeostasis. Tissue types that express this protein have been reported in the muscle, brain, neuroendocrine organs, and kidney.In normal kidney, parvalbumin has been shown to be limited to the distal tubular and collecting duct cells (the intercalated cells). Parvalbumin is strongly expressed in almost all primary, as well as metastatic, chromophobe renal cell carcinoma (RCC) (100%) and oncocytoma (69%), but is essentially negative in other types of RCCs, such as clear cell RCC and papillary RCC. This limited expression has been considered in keeping with the putative histogenesis of chromophobe RCC and oncocytoma from the distal portion of the nephron and may facilitate in their differential diagnoses.

Qualität

IVD

IVD

IVD

RUO

Verlinkung

Parvalbumin Positive Control Slides, Product No. 396S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Physikalische Form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Angaben zur Herstellung

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Sonstige Hinweise

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Rechtliche Hinweise

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany