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38790

Sigma-Aldrich

(±)-Pinostrobin

≥99.0% (TLC)

Synonym(e):

(RS)-2,3-Dihydro-5-hydroxy-7-methoxy-2-phenyl-4H-1-benzopyran-4-on

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About This Item

Empirische Formel (Hill-System):
C16H14O4
CAS-Nummer:
75291-74-6
Molekulargewicht:
270.28
MDL-Nummer:
MFCD00017481
UNSPSC-Code:
12352200
PubChem Substanz-ID:
329755783
NACRES:
NA.25

Qualitätsniveau

100

Assay

≥99.0% (TLC)

SMILES String

COc1cc(O)c2C(=O)CC(Oc2c1)c3ccccc3

InChI

1S/C16H14O4/c1-19-11-7-12(17)16-13(18)9-14(20-15(16)8-11)10-5-3-2-4-6-10/h2-8,14,17H,9H2,1H3

InChIKey

ORJDDOBAOGKRJV-UHFFFAOYSA-N

Anwendung

(±)-Pinostrobin, a chiral flavonoid (±), may be used in the development of analytical methods for separation of its individual enantiomers. Pinostrobin may be used to study its neuroprotective antioxidant effects.

Verpackung

Bottomless glass bottle. Contents are inside inserted fused cone.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Quercetin ≥95% (HPLC), solid

Sigma-Aldrich

Q4951

Quercetin

Alka Jaudan et al.
PloS one, 13(2), e0191523-e0191523 (2018-02-09)
Pinostrobin (PN) is a naturally occurring dietary bioflavonoid, found in various medicinal herbs/plants. Though anti-cancer potential of many such similar constituents has been demonstrated, critical biochemical targets and exact mechanism for their apoptosis-inducing actions have not been fully elucidated. The
Yan-Fang Xian et al.
Cellular and molecular neurobiology, 32(8), 1223-1230 (2012-05-09)
Beta-Amyloid peptide (Aβ), a major protein component of brain senile plaques in Alzheimer's disease (AD), has been considered as a critical cause in the pathogenesis of AD. Pinostrobin, a potent flavonoid inducer, is the major and most active ingredient of
Monika Asztemborska et al.
Electrophoresis, 24(15), 2527-2531 (2003-08-06)
Micellar electrokinetic chromatography (MEKC) was applied for enantioseparation of selected flavanones, including naringin, hesperidin, neohesperidin, naringenin, hesperetin, pinostrobin, isosakuranetin, eriodictyol, and homoeriodictyol. gamma-Cyclodextrin (gamma-CD) and sodium cholate (SCh) were used as chiral modifiers inducing enantioselectivity to the background electrolyte. From
Stereospecific analytical method development and preliminary in vivo pharmacokinetic characterization of pinostrobin in the rat.
Sayre CL, Zhang Y, Martinez SE, et al.
Biomedical Chromatography (2012)
Karen J Marsh et al.
Phytochemistry, 160, 31-39 (2019-01-27)
A group of plant specialised metabolites (PSMs) collectively known as unsubstituted B-ring flavanones (UBFs) have previously been found in the foliage of some species from the genus Eucalyptus L'Hér. (Myrtaceae), specifically from the subgenus Eucalyptus (monocalypts). Captive feeding studies using
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