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36799

Sigma-Aldrich

7-(Diethylamino)cumarin-3-carbonsäure

BioReagent, suitable for fluorescence, ≥98.0% (HPCE)

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About This Item

Empirische Formel (Hill-System):
C14H15NO4
CAS-Nummer:
50995-74-9
Molekulargewicht:
261.27
Beilstein:
6145963
MDL-Nummer:
MFCD00068721
UNSPSC-Code:
12352106
PubChem Substanz-ID:
57649663
NACRES:
NA.32

Produktlinie

BioReagent

Assay

≥98.0% (HPCE)

mp (Schmelzpunkt)

222-224 °C (dec.) (lit.)

Löslichkeit

DMF: soluble
DMSO: soluble

Fluoreszenz

λex 409 nm; λem 473 nm in 0.1 M Tris pH 9.0

Eignung

suitable for fluorescence

SMILES String

CCN(CC)c1ccc2C=C(C(O)=O)C(=O)Oc2c1

InChI

1S/C14H15NO4/c1-3-15(4-2)10-6-5-9-7-11(13(16)17)14(18)19-12(9)8-10/h5-8H,3-4H2,1-2H3,(H,16,17)

InChIKey

WHCPTFFIERCDSB-UHFFFAOYSA-N

Anwendung

7-(Diethylamino)coumarin-3-carboxylic acid (7-DCCA) may be used to study its photophysical properties in various solvents and solvent mixtures and as a fluorescent label for amine modification and protein conjugation

Verpackung

Bottomless glass bottle. Contents are inside inserted fused cone.

Sonstige Hinweise

Fluoreszenzlabel für Aminmodifikation und Konjugation mit Proteinen.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)

Analysenzertifikate (COA)

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Alicia S Kriete et al.
Interface focus, 9(4), 20190013-20190013 (2019-07-03)
Urinary incontinence is a significant challenge for women who are affected by it. We propose augmenting the tissue structure to restore normal biomechanics by molecularly engineering the tissue using a novel family of biomimetic proteoglycans (BPGs). This work examines the
Simone Kunzelmann et al.
Biochemistry, 49(5), 843-852 (2009-12-24)
A single-stranded DNA binding protein (SSB), labeled with a fluorophore, interacts with single-stranded DNA (ssDNA), giving a 6-fold increase in fluorescence. The labeled protein is the adduct of the G26C mutant of the homotetrameric SSB from Escherichia coli and a
J R Leisey et al.
The American journal of physiology, 267(2 Pt 2), H645-H653 (1994-08-11)
Quantitation of metabolic parameters using the technique of cardiac surface fluorescence is complicated by motion and changes in tissue absorption. Because ratio fluorescence methodology can be applied to eliminate motion-induced errors, in the current study, we used a ratio fluorescence
A Kakio et al.
The Journal of biological chemistry, 276(27), 24985-24990 (2001-05-09)
GM1 ganglioside-bound amyloid beta-protein (GM1/Abeta), found in brains exhibiting early pathological changes of Alzheimer's disease (AD) including diffuse plaques, has been suggested to be involved in the initiation of amyloid fibril formation in vivo by acting as a seed. To
Rosaria Notariale et al.
Acta biochimica Polonica, 65(4), 585-594 (2018-11-18)
The major acid-soluble protein components of the mussel Mytilus galloprovincialis sperm chromatin consist of the protamine-like proteins PL-II, PL-III and PL-IV, an intermediate group of sperm nuclear basic proteins between histones and protamines. The aim of this study was to
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