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Merck

19699

Sigma-Aldrich

cis-2-Decensäure

≥95.0% (HPLC)

Synonym(e):

2-Decenoic acid, (2Z)-

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About This Item

Empirische Formel (Hill-System):
C10H18O2
CAS-Nummer:
Molekulargewicht:
170.25
Beilstein:
1721990
MDL-Nummer:
UNSPSC-Code:
12352211
PubChem Substanz-ID:
NACRES:
NA.25

Assay

≥95.0% (HPLC)
95.0-105.0% (T)

Form

liquid

Funktionelle Gruppe

carboxylic acid

Lipid-Typ

unsaturated FAs

Lagertemp.

−20°C

SMILES String

CCCCCCC\C=C/C(O)=O

InChI

1S/C10H18O2/c1-2-3-4-5-6-7-8-9-10(11)12/h8-9H,2-7H2,1H3,(H,11,12)/b9-8-

InChIKey

WXBXVVIUZANZAU-HJWRWDBZSA-N

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Anwendung

cis-2-Decenoic acid may be used to study its cytotoxic effect on the human HepG2 cell line. It has also been used to study its synergistic anti-spirochetal effect.

Biochem./physiol. Wirkung

cis-2-Decenoic acid is a fatty acid messenger (signaling molecule) produced by Pseudomonas aeruginosa. It possesses anti-biofilm property and converts most of the cells to planktonic (free-swimming) phenotype. cis-2-Decenoic acid retains the susceptibility of the bacteria towards antimicrobial agents. It does not exhibit any toxicity towards human cells and thus, might be used for treating biofilm-associated infections. cis-2-Decenoic acid is considered active even in nano-molar ranges. It mediates the transition of dormant P. aeruginosa and Escherichia coli to their biologically active state without affecting the number of cells. cis-2-Decenoic acid is effective against E. coli and Klebsiella pneumoniae mixed-species biofilms when used along with antimicrobial agents.

Verpackung

Bottomless glass bottle. Contents are inside inserted fused cone.

Piktogramme

Exclamation mark

Signalwort

Warning

Gefahreneinstufungen

Aquatic Chronic 3 - Eye Irrit. 2 - Skin Irrit. 2

Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 1


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