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Merck

10810

Sigma-Aldrich

β-Apo-8′-carotinal (trans)

≥96.0% (UV)

Synonym(e):

Apocarotinal

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About This Item

Empirische Formel (Hill-System):
C30H40O
CAS-Nummer:
Molekulargewicht:
416.64
Beilstein:
2064131
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
12352205
PubChem Substanz-ID:
NACRES:
NA.79

Biologische Quelle

synthetic

Assay

≥96.0% (UV)

Form

powder

Verlust

≤0.5% loss on drying, 20 °C (HV)

mp (Schmelzpunkt)

137-141 °C

Löslichkeit

chloroform: 1 mg/mL, clear to very faintly turbid, intense red-orange

Lagertemp.

−20°C

SMILES String

[H]C(=O)\C(C)=C\C=C\C(C)=C\C=C\C=C(C)\C=C\C=C(C)\C=C\C1=C(C)CCCC1(C)C

InChI

1S/C30H40O/c1-24(13-8-9-14-25(2)16-11-18-27(4)23-31)15-10-17-26(3)20-21-29-28(5)19-12-22-30(29,6)7/h8-11,13-18,20-21,23H,12,19,22H2,1-7H3/b9-8+,15-10+,16-11+,21-20+,24-13+,25-14+,26-17+,27-18+

InChIKey

DFMMVLFMMAQXHZ-DOKBYWHISA-N

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Anwendung


  • Tackling the challenge of selective analytical clean-up of complex natural extracts: the curious case of chlorophyll removal: This study outlines a methodology for the selective analytical clean-up of complex natural extracts, which can be applied to enhance the purity and stability of trans-β-Apo-8′-carotenal, particularly useful in the context of life science manufacturing and research and development. This approach is crucial for maintaining the integrity of bioactive compounds during synthesis and storage (Bijttebier et al., 2014).

Biochem./physiol. Wirkung

Natural carotenoid that is formed from β-carotene in vivo and is an inducer of cytochrome P450 1A (CYP1A) in rats and in Ah-receptor-responsive mice.

Sonstige Hinweise

Internal standard in the detection of citrus carotenoids by reversed-phase HPLC

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 2

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)


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Yuka Matsushita-Ishiodori et al.
Biochemical and biophysical research communications, 359(1), 157-162 (2007-05-29)
Mutations in human spastin (SPG4) cause an autosomal dominant form of hereditary spastic paraplegia. Sequence analysis revealed that spastin contains the AAA (ATPases associated with diverse cellular activities) domain in the C-terminal region. Recently, it was reported that spastin interacts
Feng Liu et al.
Proteomics, 6(9), 2673-2692 (2006-04-06)
Hematopoietic stem cells are capable of self-renewal and differentiation into different hematopoietic lineages. To gain a comprehensive understanding of hematopoietic stem/progenitor cells, a systematic proteomic survey of human CD34+ cells collected from human umbilical cord blood was performed, in which
C Duszka et al.
The Journal of nutrition, 126(10), 2550-2556 (1996-10-01)
The purposes of this study were to determine the location of beta-carotene dioxygenase (EC 1.13.11.21) activity within the rat gastrointestinal tract, within the villus and within enterocytes, and to identify the metabolites produced in each intestinal fraction. In Wistar female
J R Kanofsky et al.
Photochemistry and photobiology, 73(4), 349-358 (2001-05-03)
A cationic carotenoid derivative (GRP-carotenal) was synthesized by the reaction of Girard's reagent P and beta-apo-8'-carotenal. The singlet-oxygen quenching constants for GRP-carotenal were 1.3 +/- 0.1 x 10(10) and 1.0 +/- 0.1 x 10(10) M-1 s-1 in acetonitrile and in
G Drikos et al.
European biophysics journal : EBJ, 16(4), 193-205 (1988-01-01)
During the visual process, light absorption in the 11-cis retinylidene chromophore leads to a rapid cis-trans-isomerization which initiates the phototransduction step. Important spectroscopic properties of this chromophore can be derived from polarized UV-absorption spectra of crystalline 11-cis-retinal if a parallel

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