Y0001754

Fluticasonpropionat für die Identifizierung von Unreinheit C

European Pharmacopoeia (EP) Reference Standard

• Synonym(e): Fluticasonpropionat, (6α,11β,16α,17α)-6,9-Difluor-11-hydroxy-16-methyl-3-oxo-17-(1-oxopropoxy)-androsta-1,4-dien-17-thiocarbonsäure-S-(fluormethyl)-ester
• Empirische Formel (Hill-System): C₂₅H₃₁F₃O₅S
• CAS-Nummer: 80474-14-2
• Molekulargewicht: 500.57
• MDL-Nummer: MFCD00866007
• UNSPSC-Code: 41116107
• PubChem Substanz-ID: 329831553
• NACRES: NA.24

Eigenschaften

• Qualität: pharmaceutical primary standard
• API-Familie: fluticasone
• Hersteller/Markenname: EDQM
• Anwendung(en): pharmaceutical (small molecule)
• Format: neat
• Lagertemp.: 2-8°C
• SMILES String: CCC(=O)O[C@@]1([C@H](C)C[C@H]2[C@@H]3C[C@H](F)C4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]12C)C(=O)SCF
• InChI: 1S/C25H31F3O5S/c1-5-20(31)33-25(21(32)34-12-26)13(2)8-15-16-10-18(27)17-9-14(29)6-7-22(17,3)24(16,28)19(30)11-23(15,25)4/h6-7,9,13,15-16,18-19,30H,5,8,10-12H2,1-4H3/t13-,15+,16+,18+,19+,22+,23+,24+,25+/m1/s1
• InChIKey: WMWTYOKRWGGJOA-CENSZEJFSA-N
• Angaben zum Gen: human ... NR3C1(2908)

Beschreibung

Allgemeine Beschreibung

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Anwendung

Fluticasone propionate for impurity C identification EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Biochem./physiol. Wirkung

Fluticasonpropionat ist ein Glucocorticoid der zweiten Generation. Es wird als entzündungshemmendes Mittel bei Asthma verwendet. Eine erhöhte konzentrationsabhängige eosinophile Apoptose über den Glucocorticoid-Rezeptor wurde gezeigt.

Verpackung

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Sonstige Hinweise

Sales restrictions may apply.

Sicherheitshinweise

• Piktogramme: GHS08
• Signalwort: Warning
• H-Sätze: H361f,H373
• P-Sätze: P202 - P260 - P280 - P308 + P313 - P405 - P501
• Gefahreneinstufungen: Repr. 2 - STOT RE 2
• Zielorgane: Endocrine system
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable