Direkt zum Inhalt
Merck
Alle Fotos(1)

Key Documents

View All Documentation

Y0000893

Imipramin für die Systemeignung

European Pharmacopoeia (EP) Reference Standard

Synonym(e):

Imipramin -hydrochlorid, 10,11-Dihydro-N,N-dimethyl-5H-dibenz[b,f]azepin-5-propanamin -hydrochlorid, 5-[3-(Dimethylamino)-propyl]-10,11-dihydro-5H-dibenz[b,f]azepin -hydrochlorid

Anmeldenzur Ansicht organisationsspezifischer und vertraglich vereinbarter Preise
Alle Fotos(1)

About This Item

Empirische Formel (Hill-System):
C19H24N2 · HCl
CAS-Nummer:
113-52-0
Molekulargewicht:
316.87
MDL-Nummer:
MFCD00012669
UNSPSC-Code:
41116107
PubChem Substanz-ID:
329831208
NACRES:
NA.24

Qualität

pharmaceutical primary standard

API-Familie

imipramine

Hersteller/Markenname

EDQM

Anwendung(en)

pharmaceutical (small molecule)

Format

neat

Lagertemp.

2-8°C

SMILES String

Cl[H].CN(C)CCCN1c2ccccc2CCc3ccccc13

InChI

1S/C19H24N2.ClH/c1-20(2)14-7-15-21-18-10-5-3-8-16(18)12-13-17-9-4-6-11-19(17)21;/h3-6,8-11H,7,12-15H2,1-2H3;1H

InChIKey

XZZXIYZZBJDEEP-UHFFFAOYSA-N

Angaben zum Gen

human ... SLC6A2(6530) , SLC6A4(6532)

Suchen Sie nach ähnlichen Produkten? Aufrufen Leitfaden zum Produktvergleich

Allgemeine Beschreibung

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Anwendung

Imipramine for system suitability EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Biochem./physiol. Wirkung

Tricyclisches Antidepressivum; hemmt die Serotonin- und Noradrenalin-Transporter mit Kis von 7.7 nM bzw. 67 nM. Hat wenig Einfluss auf Dopamin-Transporter (Ki = 25 μM).

Verpackung

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Sonstige Hinweise

Sales restrictions may apply.

Piktogramme

Skull and crossbones
GHS06

Signalwort

Danger

H-Sätze

H300

Gefahreneinstufungen

Acute Tox. 2 Oral

Lagerklassenschlüssel

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 1

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Hier finden Sie alle aktuellen Versionen:

Analysenzertifikate (COA)

Lot/Batch Number

Leider sind derzeit keine COAs für dieses Produkt online verfügbar.

Wenn Sie Hilfe benötigen, wenden Sie sich bitte an Kundensupport

Besitzen Sie dieses Produkt bereits?

In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

Ritabrata Banerjee et al.
Psychiatry investigation, 11(3), 297-306 (2014-08-12)
The present study aimed to investigate whether graded doses of Bacopa Monniera (BM) extract could produce antidepressant-like effects in chronic unpredictable stress (CUS) induced depression in rats and its possible mechanism(s). Rats were subjected to an experimental setting of CUS.
Kazumi Miyawaki et al.
Journal of pharmacological sciences, 127(3), 382-390 (2015-04-04)
Biological rhythms are critical in the etiology of mood disorders; therefore, effective mood disorder treatments should address rhythm disturbances. Among the variables synchronized with the light-dark cycle, spontaneous activity in rodents is useful for investigating circadian rhythms. However, previous studies
Helena Domin et al.
Behavioural brain research, 273, 23-33 (2014-07-22)
The glutamatergic predominance in the excitatory-inhibitory balance is postulated to be involved in the pathogenesis of depression. Such imbalance may be induced by astrocyte ablation which reduces glutamate uptake and increases glutamate level in the synaptic cleft. In the present
Juliana O G Nascimento et al.
Brain research bulletin, 109, 39-45 (2014-10-08)
The dorsomedial hypothalamus (DMH) has long been associated with the regulation of escape, a panic-related defensive response. Previous evidence has shown that the activation of serotonin (5-HT) 1A and 2A receptors impairs escape behavior induced by the electrical stimulation of
Gu Ping et al.
Pharmacology, biochemistry, and behavior, 124, 5-12 (2014-05-23)
Valsartan is a synthetic non-peptide angiotensin II type 1 receptor antagonist that dilates blood vessels and reduces blood pressure by blocking the action of angiotensin, and is safe and well tolerated in hypertensive patients. Population-based studies have suggested a positive
Alle zugehörigen Dokumente anzeigen

Unser Team von Wissenschaftlern verfügt über Erfahrung in allen Forschungsbereichen einschließlich Life Science, Materialwissenschaften, chemischer Synthese, Chromatographie, Analytik und vielen mehr..

Setzen Sie sich mit dem technischen Dienst in Verbindung.