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Merck

SMB00978

Sigma-Aldrich

L-Hercynine

≥95% (HPLC)

Synonym(e):

α-N,N,N-Trimethylhistidine, N-α-trimethyl histidine, Histidine-betaine

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About This Item

Empirische Formel (Hill-System):
C9H15N3O2
CAS-Nummer:
Molekulargewicht:
197.23
NACRES:
NA.26

Qualitätsniveau

Assay

≥95% (HPLC)

Form

solid

Lagertemp.

2-8°C

SMILES String

C[N+](C)(C)[C@H](C([O-])=O)CC1=CN=CN1

InChI

1S/C9H15N3O2/c1-12(2,3)8(9(13)14)4-7-5-10-6-11-7/h5-6,8H,4H2,1-3H3,(H-,10,11,13,14)/t8-/m0/s1

InChIKey

GPPYTCRVKHULJH-QMMMGPOBSA-N

Allgemeine Beschreibung

Hercynine is the precursor and redox metabolite of ergothioneine, which regulates microbial physiology and enables the survival of microbes under stressful conditions encountered in their natural environments. Ergothioneine is primarily present as a thione physiological pH, which makes it resistant to autoxidation. Ergothioneine enables pathogenic microbes, such as Mycobacterium tuberculosis (Mtb) to withstand hostile environments within the host to establish infection.

Anwendung

Hercynine is a versatile molecule and it finds application in biochemical and metabolomics research.

Leistungsmerkmale und Vorteile

  • Can be used in Metabolomics and Biochemical research
  • High-quality compound suitable for multiple research applications

Sonstige Hinweise

For additional information on our range of Biochemicals, please complete this form.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


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Analysenzertifikate (COA)

Lot/Batch Number

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In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

Salvatore Sotgia et al.
Antioxidants (Basel, Switzerland), 9(9) (2020-09-17)
The dependence of a stallion's spermatozoa on oxidative phosphorylation for energy requirements results in an unconventional relationship between reactive oxygen species (ROS) production and fertility. In such a scenario, antioxidant activity must be finely controlled and not affect the essential
Tomoyuki Kamide et al.
Journal of agricultural and food chemistry, 68(23), 6390-6394 (2020-05-22)
We previously constructed a heterologous production system for ergothioneine (ERG) in Escherichia coli using five ERG biosynthesis genes (egtABCDE) from Mycobacterium smegmatis. However, significant amounts of hercynine (HER), an intermediate of ERG, as ERG were accumulated, suggesting that the reaction

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