PHR1424

Ampicillin-Natrium

Pharmaceutical Secondary Standard; Certified Reference Material

• Synonym(e): Ampicillin Natriumsalz, D-(−)-α-Aminobenzylpenicillin Natriumsalz
• Empirische Formel (Hill-System): C₁₆H₁₈N₃NaO₄S
• CAS-Nummer: 69-52-3
• Molekulargewicht: 371.39
• Beilstein: 4119211
• EG-Nummer: 200-708-1
• MDL-Nummer: MFCD00064313
• UNSPSC-Code: 41116107
• PubChem Substanz-ID: 329822591
• NACRES: NA.24

Eigenschaften

• Qualität: certified reference material; pharmaceutical secondary standard
• Qualitätsniveau: 300
• Agentur: traceable to BP 785; traceable to Ph. Eur. A1000000; traceable to USP 1033203
• API-Familie: ampicillin
• Analysenzertifikat (CofA): current certificate can be downloaded
• Methode(n): HPLC: suitable; gas chromatography (GC): suitable
• mp (Schmelzpunkt): 215 °C (dec.) (lit.)
• Anwendung(en): pharmaceutical (small molecule)
• Format: neat
• Lagertemp.: 2-30°C
• SMILES String: [Na+].CC1(C)SC2[C@H](NC(=O)[C@H](N)c3ccccc3)C(=O)N2[C@H]1C([O-])=O
• InChI: 1S/C16H19N3O4S.Na/c1-16(2)11(15(22)23)19-13(21)10(14(19)24-16)18-12(20)9(17)8-6-4-3-5-7-8;/h3-7,9-11,14H,17H2,1-2H3,(H,18,20)(H,22,23);/q;+1/p-1/t9-,10-,11+,14-;/m1./s1
• InChIKey: KLOHDWPABZXLGI-YWUHCJSESA-M

Beschreibung

Allgemeine Beschreibung

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Anwendung

Ampicillin Sodium may be used as a pharmaceutical secondary reference standard for the determination of the analyte in pharmaceutical formulations by high performance liquid chromatography with ultra violet detection and second-derivative spectrophotometry, respectively.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Biochem./physiol. Wirkung

Wirkungsweise: Dieses Produkt ist ein ß-Lactam-Antibiotikum, das die Zellwandsynthese von Bakterien hemmt, indem es Transpeptidasen auf der Innenoberfläche der Zellmembran der Bakterien deaktiviert.

Wirkungsweise der Resistenz: Die Verabreichung zusammen mit ß-Lactamase spaltet den ß-Lactam-Ring von Ampicillin und deaktiviert ihn.

Antimikrobielles Spektrum: Enthält sowohl grampositive (Benzylpenicillin-ähnliche) wie auch gramnegative (Tetracyclin- und Chloramphenicol-ähnliche) Bakterien.

Hinweis zur Analyse

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Sonstige Hinweise

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Fußnote

To see an example of a Certificate of Analysis for this material enter LRAA2732 in the slot below. This is an example certificate only and may not be the lot that you receive.

Sicherheitshinweise

• Piktogramme: GHS08
• Signalwort: Danger
• H-Sätze: H317,H334
• P-Sätze: P261 - P280 - P342 + P311
• Gefahreneinstufungen: Resp. Sens. 1 - Skin Sens. 1
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 2
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable