PHL89151

Acetoxyvalerensäure

phyproof^® Reference Substance

• Synonym(e): Acetylvalerenolsäure
• Empirische Formel (Hill-System): C₁₇H₂₄O₄
• CAS-Nummer: 84638-55-1
• Molekulargewicht: 292.37
• MDL-Nummer: MFCD03093738
• UNSPSC-Code: 41116107
• NACRES: NA.24

Eigenschaften

• Qualität: primary reference standard
• Produktlinie: phyproof^® Reference Substance
• Assay: ≥95.0% (HPLC)
• Hersteller/Markenname: PhytoLab
• Anwendung(en): food and beverages
• Format: neat
• Lagertemp.: −20°C
• SMILES String: C[C@@H]1CC[C@@H](\C=C(/C)C(O)=O)C2=C(C)C[C@@H](OC(C)=O)[C@H]12
• InChI: 1S/C17H24O4/c1-9-5-6-13(7-11(3)17(19)20)15-10(2)8-14(16(9)15)21-12(4)18/h7,9,13-14,16H,5-6,8H2,1-4H3,(H,19,20)/b11-7+/t9-,13+,14-,16+/m1/s1
• InChIKey: VBBXZFLAYWAXSK-HYJCDKNOSA-N

Beschreibung

Allgemeine Beschreibung

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

Anwendung

• Acetoxyvalerenic acid in bioactive spectral analysis: Research demonstrated the use of ATR-FTIR spectroscopy for quality control of Valerianae Radix, potentially including compounds like Acetoxyvalerenic acid, to ensure the bioactive natural compounds meet pharmaceutical standards (Nikzad-Langerodi et al., 2018).
• Pharmacokinetics of valerenic derivatives: A study on the pharmacokinetics of valerenic acid, closely related to Acetoxyvalerenic acid, in older women illustrates its bioavailability and potential as a GABAergic activity modulator, which is crucial for developing sedative pharmaceuticals (Anderson et al., 2010).
• Enhancement of sesquiterpenic acids in Valeriana officinalis: Research showed that root colonization by arbuscular mycorrhizal fungi increases the concentrations of sesquiterpenic acids, including potentially Acetoxyvalerenic acid, emphasizing its importance in valerian derivative biochemical studies (Nell et al., 2010).
• Acetoxyvalerenic acid in blood-brain barrier studies: A study investigated the transport of GABAA receptor modulators across the blood-brain barrier, relevant for compounds like Acetoxyvalerenic acid, providing key insights into its neuropharmacological applications (Neuhaus et al., 2008).
• GABAA receptor modulation by valerian extracts: The modulation of GABAA receptors by valerian extracts was found to be correlated with the content of valerenic acid, which includes derivatives like Acetoxyvalerenic acid, indicating its potential use in natural sedative compound research (Trauner et al., 2008).

Sonstige Hinweise

This compound is commonly found in plants of the genus: valeriana

Rechtliche Hinweise

phyproof is a registered trademark of PhytoLab GmbH & Co. KG

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable