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Merck

P4272

Sigma-Aldrich

3-(2-Pyridyl)-5,6-di(2-furyl)-1,2,4-Triazin-5′,5′′-Disulfonsäure Dinatriumsalz

Powder or crystals

Synonym(e):

5,5′-[3-(2-Pyridyl)-1,2,4-triazin-5,6-diyl]-difuran-2-sulfonsäure Dinatriumsalz

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About This Item

Empirische Formel (Hill-System):
C16H8N4Na2O8S2
CAS-Nummer:
Molekulargewicht:
494.37
Beilstein:
5710932
MDL-Nummer:
UNSPSC-Code:
12171500
PubChem Substanz-ID:
NACRES:
NA.47

product name

3-(2-Pyridyl)-5,6-di(2-furyl)-1,2,4-Triazin-5′,5′′-Disulfonsäure Dinatriumsalz, Suitable for determination of Fe

Qualitätsniveau

Form

powder or crystals

Zusammensetzung

Water: ≤ 13.0%

Carbon (Theory), anhydrous: 38.87%

Nitrogen (Theory), anhydrous: 11.33%

Methode(n)

titration: suitable

Farbe

white to dark yellow

Löslichkeit

water: 50 mg/mL, clear to slightly hazy

Kationenspuren

C: 38.87% ((Theory), anhydrous)
N: 11.33% ((Theory), anhydrous)

Eignung

suitable for determination of iron

Anwendung(en)

diagnostic assay manufacturing
hematology
histology

Lagertemp.

room temp

SMILES String

[Na+].[Na+].[O-]S(=O)(=O)c1ccc(o1)-c2nnc(nc2-c3ccc(o3)S([O-])(=O)=O)-c4ccccn4

InChI

1S/C16H10N4O8S2.2Na/c21-29(22,23)12-6-4-10(27-12)14-15(11-5-7-13(28-11)30(24,25)26)19-20-16(18-14)9-3-1-2-8-17-9;;/h1-8H,(H,21,22,23)(H,24,25,26);;/q;2*+1/p-2

InChIKey

IVLSEFOVPQFJBB-UHFFFAOYSA-L

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Allgemeine Beschreibung

3-(2-Pyridyl)-5,6-di(2-furyl)-1,2,4-triazine-5′,5′′-disulfonic acid disodium salt, also known as Ferene, is commonly used to measure the concentration of iron ions in aqueous solutions. The reagent is sensitive to ferrous iron ions (Fe2+) and forms a purple-colored complex with these ions in the presence of a reducing agent. The intensity of the purple color formed is proportional to the concentration of iron ions present in a solution and is quantified spectrophotometrically.

Anwendung

3-(2-Pyridyl)-5,6-di(2-furyl)-1,2,4-triazine-5′,5′′-disulfonic acid disodium salt has been used as a component in a sensitive colorimetric assay (ferene-s assay) for the detection of iron.

Piktogramme

Exclamation mark

Signalwort

Warning

Gefahreneinstufungen

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Zielorgane

Respiratory system

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

dust mask type N95 (US), Eyeshields, Gloves


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Novel chromogen for serum iron determinations.
T Higgins
Clinical chemistry, 27(9), 1619-1620 (1981-09-01)
L M Leong et al.
Analytical biochemistry, 207(2), 317-320 (1992-12-01)
Nonheme iron proteins can be visualized as blue bands in native polyacrylamide gels using a staining method that is both simple and rapid. The reaction of potassium ferricyanide with protein-bound iron atoms to form royal blue complexes occurs almost instantaneously
J M Gutteridge
Journal of trace elements and electrolytes in health and disease, 5(4), 271-272 (1991-12-01)
Superoxide and hydrogen peroxide are often ascribed iron reducing roles in reactions leading to the formation of an aggressive oxidant by Fenton Chemistry. Hydrogen peroxide, however, does not appear to reduce iron in Fenton reactions, and we here show that
J D Artiss et al.
American journal of clinical pathology, 108(3), 269-274 (1997-09-18)
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D Krzyzanowska et al.
Biological chemistry, 382(7), 1027-1037 (2001-09-04)
It has been previously suggested that juvenile hormone binding protein(s) (JHBP) belongs to a new class of proteins. In the search for other protein(s) that may contain structural motifs similar to those found in JHBP, hemolymph from Galleria mellonella (Lepidoptera)

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