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Dokumente

B9050

Sigma-Aldrich

Benoxinat -hydrochlorid

meets USP testing specifications

Synonym(e):

4-Amino-3-butoxybenzoesäure-[2-(diethylamino)-ethyl]-ester -hydrochlorid, Oxybuprocain -hydrochlorid

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About This Item

Empirische Formel (Hill-System):
C17H28N2O3 · HCl
CAS-Nummer:
5987-82-6
Molekulargewicht:
344.88
EG-Nummer:
227-808-8
MDL-Nummer:
MFCD00012512
UNSPSC-Code:
41116107
PubChem Substanz-ID:
24892118
NACRES:
NA.21

Agentur

USP/NF
meets USP testing specifications

Qualitätsniveau

200

Form

solid

Anwendung(en)

pharmaceutical (small molecule)

SMILES String

Cl[H].CCCCOc1cc(ccc1N)C(=O)OCCN(CC)CC

InChI

1S/C17H28N2O3.ClH/c1-4-7-11-21-16-13-14(8-9-15(16)18)17(20)22-12-10-19(5-2)6-3;/h8-9,13H,4-7,10-12,18H2,1-3H3;1H

InChIKey

PRGUDWLMFLCODA-UHFFFAOYSA-N

Angaben zum Gen

human ... SCN10A(6336) , SCN11A(11280) , SCN1A(6323) , SCN2A(6326) , SCN3A(6328) , SCN4A(6329) , SCN5A(6331) , SCN7A(6332) , SCN8A(6334) , SCN9A(6335)

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Lagerklassenschlüssel

13 - Non Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

dust mask type N95 (US), Eyeshields, Gloves

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Analysenzertifikate (COA)

Lot/Batch Number
BCBL6676V
BCBL3297V
BCBL2681V
BCBK9870V
BCBJ3633V

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Shai Sandalon et al.
Documenta ophthalmologica. Advances in ophthalmology, 118(2), 101-108 (2008-07-31)
Topical anesthetics are recommended when electroretinograms (ERGs) are recorded using contact lens electrodes. However, these drugs act by blocking voltage-gated Na+ channels. Since such channels have been located in both the inner and outer retina of many species, topical anesthesia
Ching-Hsia Hung et al.
Neuroscience letters, 454(3), 249-253 (2009-05-12)
Proxymetacaine and oxybuprocaine were clinically used for topical ocular anesthesia but never for spinal anesthesia, and therefore spinal anesthetic effects of proxymetacaine and oxybuprocaine were performed and compared with bupivacaine and lidocaine. After rats were injected intrathecally with proxymetacaine, oxybuprocaine
Yakov Goldich et al.
Cornea, 30(1), 105-106 (2010-09-18)
To report the diagnosis and management of a patient with chronic ophthalmic topical anesthetic abuse and floppy eyelid syndrome. We describe the case of a 47-year-old man suffering from persistent bilateral ocular irritation and chronic corneal erosions. The patient was
Srinivas K Rao et al.
Journal of cataract and refractive surgery, 33(8), 1482-1484 (2007-07-31)
A 42-year-old woman had uneventful bilateral laser-assisted subepithelial keratectomy (LASEK) to correct myopia. She experienced intense pain in the first postoperative week and obtained topical oxybuprocaine for pain relief. Subsequently, she developed bilateral persistent corneal epithelial defects, epithelial edema, and
Bingsong Wang et al.
Journal of glaucoma, 24(6), 433-437 (2015-08-01)
To study the association between the insertion location of iris root and narrow angle. This was a prospective observational study. A total of 142 eyes of 142 subjects were recruited, including 78 with narrow angles and 64 normals. All participants
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