75580

Triethylorthoacetat

purum, ≥98.0% (GC)

• Synonym(e): Triethyl-orthoacetat
• Lineare Formel: CH₃C(OC₂H₅)₃
• CAS-Nummer: 78-39-7
• Molekulargewicht: 162.23
• Beilstein: 506201
• EG-Nummer: 201-112-4
• MDL-Nummer: MFCD00009223
• UNSPSC-Code: 12352100
• PubChem Substanz-ID: 329766140
• NACRES: NA.22

Eigenschaften

• Qualität: purum
• Qualitätsniveau: 200
• Assay: ≥98.0% (GC)
• Form: liquid
• Brechungsindex: n20/D 1.396 (lit.); n20/D 1.396
• bp: 142 °C (lit.)
• Dichte: 0.885 g/mL at 25 °C (lit.)
• Funktionelle Gruppe: ether
• SMILES String: CCOC(C)(OCC)OCC
• InChI: 1S/C8H18O3/c1-5-9-8(4,10-6-2)11-7-3/h5-7H2,1-4H3
• InChIKey: NDQXKKFRNOPRDW-UHFFFAOYSA-N

Beschreibung

Anwendung

Triethyl orthoacetate is a general reagent used to functionalize alcohols with acetate groups. It can be used in following reactions:

• Stereocontrolled total synthesis of a naturally occuring indole alkaloid, (−)-aspidophytine.
• Conversion of allylic alcohols to γ,δ-unsaturated esters under mild acidic condition, a reaction popularly known as Johnson–Claisen rearrangement.
• Synthesis of heterocycles such as 2-oxazolines and quinazolin-4(3H)-one derivatives.

Sicherheitshinweise

• Piktogramme: GHS02
• Signalwort: Warning
• H-Sätze: H226
• P-Sätze: P210
• Gefahreneinstufungen: Flam. Liq. 3
• Lagerklassenschlüssel: 3 - Flammable liquids
• WGK: WGK 1
• Flammpunkt (°F): 102.2 °F - Non-equilibrium method
• Flammpunkt (°C): 39 °C - Non-equilibrium method
• Persönliche Schutzausrüstung: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter