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Merck

46648

Supelco

Praziquantel

VETRANAL®, analytical standard

Synonym(e):

2-(Cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro-4H-pyrazino[2,1-a]isochinolin-4-on

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About This Item

Empirische Formel (Hill-System):
C19H24N2O2
CAS-Nummer:
Molekulargewicht:
312.41
Beilstein:
761557
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
41116107
PubChem Substanz-ID:
NACRES:
NA.24

Qualität

analytical standard

Qualitätsniveau

Produktlinie

VETRANAL®

Haltbarkeit

limited shelf life, expiry date on the label

Methode(n)

HPLC: suitable
gas chromatography (GC): suitable

Wirkungsspektrum von Antibiotika

parasites

Anwendung(en)

clinical testing

Format

neat

Wirkungsweise

cell membrane | interferes

Lagertemp.

2-8°C

SMILES String

O=C1CN(CC2N1CCc3ccccc23)C(=O)C4CCCCC4

InChI

1S/C19H24N2O2/c22-18-13-20(19(23)15-7-2-1-3-8-15)12-17-16-9-5-4-6-14(16)10-11-21(17)18/h4-6,9,15,17H,1-3,7-8,10-13H2

InChIKey

FSVJFNAIGNNGKK-UHFFFAOYSA-N

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Allgemeine Beschreibung

Chemical structure: quinolone
Praziquantel (PZQ) is a pyrazino-isoquinoline compound used as a broad-spectrum anthelmintic drug against trematode and cestode infections.

Anwendung

PZQ may be used as a reference standard for the determination for PZQ in:
  • Surface water samples by solid phase extraction (SPE) and ultra-high performance liquid chromatography-quadrupole linear ion trap tandem mass spectrometry (UHPLC-QqLIT-MS) equipped with electrospray ionization (ESI) source.
  • Plants by HPLC with triple quadrupole mass spectrometry (HPLC-ESI-QqQ-MS/MS) operating in multiple reaction monitoring (MRM) mode.
  • Tablet formulations by reversed phase (RP) HPLC with ultraviolet (UV) detection.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Rechtliche Hinweise

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

H-Sätze

P-Sätze

Gefahreneinstufungen

Aquatic Chronic 3

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 1

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)


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Analysenzertifikate (COA)

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Die Dokumentenbibliothek aufrufen

Chromatographic separation of racemic praziquantel and its residual determination in perch by LC-MS/MS.
He L, et al.
Talanta, 174, 380-386 (2017)
Development and validation of a dissolution test method for albendazole and praziquantel in their combined dosage form.
Vignaduzzo S, et al.
Journal of the Brazilian Chemical Society, 26(4), 729-735 (2015)
Development and validation of an enantioselective LC-MS/MS method for the analysis of the anthelmintic drug praziquantel and its main metabolite in human plasma, blood and dried blood spots.
Meister I, et al.
Journal of Pharmaceutical and Biomedical Analysis, 118, 81-88 (2016)
A rapid stability indicating LC-method for determination of praziquantel in presence of its pharmacopoeial impurities.
Hashem H, et al.
Arabian Journal of Chemistry, 10, S35-S41 (2017)
Study of praziquantel phytoremediation and transformation and its removal in constructed wetland.
Marsik P, et al.
Journal of Hazardous Materials, 323, 394-399 (2017)

Protokolle

Praziquantel Determination in Aquarium Water- Learn how the use of a Chromolith® monolithic silica column allows simplification of sample preparation.

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