34088

Nitroxinil

VETRANAL^®, analytical standard

• Synonym(e): 4-Hydroxy-3-iod-5-nitrobenzonitril, Nitroxynil
• Empirische Formel (Hill-System): C₇H₃IN₂O₃
• CAS-Nummer: 1689-89-0
• Molekulargewicht: 290.01
• EG-Nummer: 216-884-8
• MDL-Nummer: MFCD00070776
• UNSPSC-Code: 41116107
• PubChem Substanz-ID: 329754805
• NACRES: NA.24

Eigenschaften

• Qualität: analytical standard
• Qualitätsniveau: 100
• Produktlinie: VETRANAL^®
• Haltbarkeit: limited shelf life, expiry date on the label
• Methode(n): HPLC: suitable; gas chromatography (GC): suitable
• Anwendung(en): forensics and toxicology; pharmaceutical (small molecule)
• Format: neat
• SMILES String: Oc1c(I)cc(cc1[N+]([O-])=O)C#N
• InChI: 1S/C7H3IN2O3/c8-5-1-4(3-9)2-6(7(5)11)10(12)13/h1-2,11H
• InChIKey: SGKGVABHDAQAJO-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

Nitroxinil is an anthelmintic agent, which is also an antiparasite. It is highly effective against Fasciola species and its mode of action involves uncoupling the oxidative phosphorylation in liver flukes and also reduces spermatogenesis in surviving flukes, resulting in fewer fertile eggs.

Anwendung

Nitroxinil may be used as a reference standard in the determination of nitroxinil in veterinary active pharmaceutical ingredient manufacturing and bovine kidney using reversed-phase high-performance liquid chromatography (RP-HPLC) and liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS).

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Rechtliche Hinweise

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Sicherheitshinweise

• Piktogramme: GHS06,GHS09
• Signalwort: Danger
• H-Sätze: H301,H315,H317,H319,H335,H400
• P-Sätze: P261 - P273 - P280 - P301 + P310 - P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Acute Tox. 3 Oral - Aquatic Acute 1 - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Persönliche Schutzausrüstung: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges