34002

(S)-(−)-Sulpirid

VETRANAL^®, analytical standard

• Synonym(e): (S)-(−)-5-(Aminosulfonyl)-N-(1-ethyl-2-pyrrolidinylmethyl)-2-methoxybenzamid, Levosulpirid
• Empirische Formel (Hill-System): C₁₅H₂₃N₃O₄S
• CAS-Nummer: 23672-07-3
• Molekulargewicht: 341.43
• MDL-Nummer: MFCD00055220
• UNSPSC-Code: 41116107
• PubChem Substanz-ID: 329754747
• NACRES: NA.24

Eigenschaften

• Qualität: analytical standard
• Qualitätsniveau: 100
• Produktlinie: VETRANAL^®
• Haltbarkeit: limited shelf life, expiry date on the label
• Methode(n): HPLC: suitable; gas chromatography (GC): suitable
• mp (Schmelzpunkt): 183-186 °C (lit.)
• Anwendung(en): forensics and toxicology; pharmaceutical (small molecule)
• Format: neat
• SMILES String: CCN1CCC[C@H]1CNC(=O)c2cc(ccc2OC)S(N)(=O)=O
• InChI: 1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21)/t11-/m0/s1
• InChIKey: BGRJTUBHPOOWDU-NSHDSACASA-N

Beschreibung

Allgemeine Beschreibung

(S)-(−)-Sulpiride is a levorotatory enantiomer of sulpiride, which shows greater central antidopaminergic activity, antiemetic and antidyspeptic effects. It is also used as a therapeutic drug for the treatment of depression and somatoform disorders.

Anwendung

(S)-(−)-Sulpiride may be used as an analytical reference standard for the determination of the drug, in biological samples using hydrophilic interaction liquid chromatography−tandem mass spectrometry (HILIC−MS/MS) and reversed-phase high-performance liquid chromatography with fluorescence detection (HPLC-FD).

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem./physiol. Wirkung

D₂ Dopamin-Rezeptor-Antagonist; antipsychotisch

Rechtliche Hinweise

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 3
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)