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Merck

32463

Supelco

5-Hydroxyflunixin

VETRANAL®, analytical standard

Synonym(e):

5-Hydroxy-2-(2-methyl-3-trifluormethylanilino)-nicotinsäure, 5-Hydroxy-2-{[2-methyl-3-(trifluormethyl)-phenyl]-amino}-3-pyridincarbonsäure

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About This Item

Empirische Formel (Hill-System):
C14H11F3N2O3
CAS-Nummer:
Molekulargewicht:
312.24
Beilstein:
9575875
MDL-Nummer:
UNSPSC-Code:
41116107
PubChem Substanz-ID:
NACRES:
NA.24

Qualität

analytical standard

Qualitätsniveau

Produktlinie

VETRANAL®

Haltbarkeit

limited shelf life, expiry date on the label

Methode(n)

HPLC: suitable
gas chromatography (GC): suitable

Anwendung(en)

forensics and toxicology
pharmaceutical (small molecule)

Format

neat

SMILES String

Cc1c(Nc2ncc(O)cc2C(O)=O)cccc1C(F)(F)F

InChI

1S/C14H11F3N2O3/c1-7-10(14(15,16)17)3-2-4-11(7)19-12-9(13(21)22)5-8(20)6-18-12/h2-6,20H,1H3,(H,18,19)(H,21,22)

InChIKey

JSXNJGKWSWRIGA-UHFFFAOYSA-N

Allgemeine Beschreibung

Flunixin (FLU) is a non-steroidal anti-inflammatory drug (NSAID). It is a nicotinic acid derivative, and is involved in inhibiting the enzyme cyclooxygenase in the arachidonic acid cascade. It is anti-pyretic and non-narcotic analgesic in nature, and finds application in veterinary medicine, where it is used to treat a wide variety of disorder in diverse species. This drug can be used to reduce pain and inflammation associated with colic in horses, musculoskeletal disorders, and infectious diseases in cattle. It can also be used as an aid in the treatment of mastitis-metritis-agalactia syndrome in sows. 5-hydroxyflunixin (5OHFLU) is the main metabolite of Flunixin (FLU).

Anwendung

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Empfohlene Produkte

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Rechtliche Hinweise

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Piktogramme

Exclamation mark

Signalwort

Warning

H-Sätze

Gefahreneinstufungen

Acute Tox. 4 Oral

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3


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Die Dokumentenbibliothek aufrufen

Shubhashis Chakrabarty et al.
Rapid communications in mass spectrometry : RCM, 34(20), e8876-e8876 (2020-07-07)
Electrospray ionization mass spectrometry (ESI-MS) in conjunction with liquid chromatography (LC) can provide accurate quantitative data, but it is not well-suited for the rapid screening (RS) of analytes incurred into complex matrices. This study was designed to determine the usefulness
M Cheema et al.
Journal of dairy science, 100(11), 8670-8679 (2017-09-18)
Casein proteins (α
Jessica L Bates et al.
BMC veterinary research, 16(1), 211-211 (2020-06-24)
Flunixin meglumine (FM) was investigated for the effectiveness of plasma, oral fluid, and urine concentrations to predict tissue residue depletion profiles in finishing-age swine, along with the potential for untreated pigs to acquire tissue residues following commingled housing with FM-treated
Weilin L Shelver et al.
Journal of agricultural and food chemistry, 64(1), 336-345 (2015-12-24)
Twenty cull dairy cows (645 ± 83 kg) were treated with 2.2 mg/kg bw flunixin by intravenous (IV) or intramuscular (IM) administration with, or without, exposure to lipopolysaccharide in a two factor balanced design. The usefulness of screening assays to

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