32138

Doripenem Monohydrat

VETRANAL^®, analytical standard

• Synonym(e): (4R,5S,6S)-6-[(1R)-1-Hydroxyethyl]-4-methyl-7-oxo-3-[(3S,5S)-5-[(sulfamoylamino)-methyl]-pyrrolidin-3-yl]-sulfanyl-1-azabicyclo[3.2.0]hept-2-en-2-carbonsäure
• Empirische Formel (Hill-System): C₁₅H₂₄N₄O₆S₂ · H₂O
• CAS-Nummer: 364622-82-2
• Molekulargewicht: 438.52
• Beilstein: 15340136
• MDL-Nummer: MFCD09749887
• UNSPSC-Code: 41116107
• PubChem Substanz-ID: 329754061
• NACRES: NA.24

Eigenschaften

• Qualität: analytical standard
• Qualitätsniveau: 100
• Produktlinie: VETRANAL^®
• Methode(n): HPLC: suitable; gas chromatography (GC): suitable
• Anwendung(en): forensics and toxicology; veterinary
• Format: neat
• Lagertemp.: 2-8°C
• SMILES String: [H]O[H].NS(NC[C@H](C1)NC[C@H]1SC2=C(C(O)=O)N3C([C@]([H])([C@H](O)C)[C@@]3([H])[C@H]2C)=O)(=O)=O
• InChI: 1S/C15H24N4O6S2.H2O/c1-6-11-10(7(2)20)14(21)19(11)12(15(22)23)13(6)26-9-3-8(17-5-9)4-18-27(16,24)25;/h6-11,17-18,20H,3-5H2,1-2H3,(H,22,23)(H2,16,24,25);1H2/t6-,7-,8+,9+,10-,11-;/m1./s1
• InChIKey: NTUBEBXBDGKBTJ-WGLOMNHJSA-N

Beschreibung

Allgemeine Beschreibung

Doripenem belongs to the carbapenems family of β-lactam antibiotic compounds.

Anwendung

Doripenem monohydrate can be used as the precursor for the preparation of doripenem which may be used as an analytical reference standard for the determination of doripenem in:

• Bovine muscle by liquid chromatography combined with tandem mass spectrometry (LC-MS/MS).
• Bulk drug and formulations by high performance thin layer chromatography (HPTLC).
• Medicinal products by capillary electrophoresis coupled to ultraviolet (UV) detector as well as micellar electrokinetic chromatography (MEKC) with UV detection.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Rechtliche Hinweise

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable