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Merck

31593

Supelco

Arecolin -hydrobromid

VETRANAL®, analytical standard

Synonym(e):

1-Methyl-1,2,5,6-tetrahydro-3-pyridincarbonsäure-methylester -hydrobromid, N-Methyltetrahydronicotinsäure-methylester -hydrobromid, Arecaidin-methylester -hydrobromid, Taeniolin

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About This Item

Empirische Formel (Hill-System):
C8H13NO2 · HBr
CAS-Nummer:
Molekulargewicht:
236.11
Beilstein:
3914826
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
41116107
PubChem Substanz-ID:
NACRES:
NA.24

Qualität

analytical standard

Qualitätsniveau

Produktlinie

VETRANAL®

Haltbarkeit

limited shelf life, expiry date on the label

Methode(n)

HPLC: suitable
gas chromatography (GC): suitable

mp (Schmelzpunkt)

172-176 °C (lit.)

Anwendung(en)

clinical
food and beverages

Format

neat

SMILES String

Br[H].COC(=O)C1=CCCN(C)C1

InChI

1S/C8H13NO2.BrH/c1-9-5-3-4-7(6-9)8(10)11-2;/h4H,3,5-6H2,1-2H3;1H

InChIKey

AXOJRQLKMVSHHZ-UHFFFAOYSA-N

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Allgemeine Beschreibung

Arecoline hydrobromide is an arecoline salt of hydrobromic acid generally used in removing parasites from dog′s intestine. It has a strong parasympathomimetic action.

Anwendung

Arecoline hydrobromide may have been used as working standard in the determination of arecoline concentration from dog plasma using LC–MS/MS.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Rechtliche Hinweise

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Piktogramme

Exclamation mark

Signalwort

Warning

H-Sätze

Gefahreneinstufungen

Acute Tox. 4 Oral

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 1

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

dust mask type N95 (US), Eyeshields, Gloves


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Analysenzertifikate (COA)

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In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

THE RELATION BETWEEN METHOD OF ADMINISTRATION, ROUTE OF ABSORPTION, INHIBITORY ACTIONS AND ACUTE TOXICITY OF ARECOLINE HYDROBROMIDE IN DOGS.
FORBES LS.
Annals of Tropical Medicine and Parasitology, 58, 119-131 (1964)
Sarah L Withey et al.
The Journal of pharmacology and experimental therapeutics, 366(2), 397-409 (2018-05-23)
Evidence suggests that the α4β2, but not the α7, subtype of the nicotinic acetylcholine receptor (nAChR) plays a key role in mediating the behavioral effects of nicotine and related drugs. However, the importance of other nAChR subtypes remains unclear. The
A Dakkak et al.
Acta tropica, 165, 26-32 (2016-07-21)
This study was undertaken in the Province of Sidi Kacem in northwest Morocco between April 2010 and March 2011. The main objective of the study was to determine the prevalence of Echinococcus granulosus (Eg) infection in owned dogs. This province
Osamu Uehara et al.
Oncology letters, 14(1), 1186-1192 (2017-07-12)
Betel quid chewing is implicated in the high prevalence of oral cancer in Southeast Asian countries. One of the major components of betel quid is arecoline. In the present study, in order to characterize the association between chronic arecoline stimulation
Vipin Jain et al.
Journal of agricultural and food chemistry, 65(9), 1977-1983 (2017-02-14)
Chewing of areca nut in different forms such as betel quid or commercially produced pan masala and gutkha is common practice in the Indian subcontinent and many parts of Asia and is associated with a variety of negative health outcomes

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