26454

Magnesiumstearat

puriss., meets analytical specification of Ph. Eur., BP, ≥90% stearic and palmitic acid basis, ≥40% stearic acid basis (GC), 4.0-5.0% Mg basis (calc on dry sub.)

• Synonym(e): Stearinsäure Magnesiumsalz
• Lineare Formel: [CH₃(CH₂)₁₆CO₂]₂Mg
• CAS-Nummer: 557-04-0
• Molekulargewicht: 591.24
• Beilstein: 3919702
• EG-Nummer: 209-150-3
• MDL-Nummer: MFCD00036391
• UNSPSC-Code: 12352106
• PubChem Substanz-ID: 57648176
• NACRES: NA.22

Eigenschaften

• Qualität: puriss.; meets analytical specification of Ph. Eur., BP
• Assay: ≥40% stearic acid basis (GC); ≥90% stearic and palmitic acid basis; 4.0-5.0% Mg basis (calc on dry sub.)
• Verunreinigungen: acidity or alkalinity, complies; microbiological impurity, in accordance; residual solvents, complies
• Verlust: ≤6.0% loss on drying, 105 °C
• mp (Schmelzpunkt): 200 °C (lit.)
• Säurezahl: 195‑210(fatty acid)
• Löslichkeit: alcohol: insoluble; diethyl ether: insoluble; water: insoluble
• Anionenspuren: chloride (Cl^-): ≤1000 mg/kg; sulfate (SO₄^2-): ≤5000 mg/kg
• Kationenspuren: Cd: ≤3 mg/kg; Ni: ≤5 mg/kg; Pb: ≤10 mg/kg
• Eignung: in accordance for fatty acid composition; passes test for identity
• Anwendung(en): pharmaceutical (small molecule)
• SMILES String: CCCCCCCCCCCCCCCCCC(=O)O[Mg]OC(=O)CCCCCCCCCCCCCCCCC
• InChI: 1S/2C18H36O2.Mg/c2*1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20;/h2*2-17H2,1H3,(H,19,20);/q;;+2/p-2
• InChIKey: HQKMJHAJHXVSDF-UHFFFAOYSA-L

Beschreibung

Anwendung

Magnesium stearate has been used as a tablet and capsule lubricant. It has also been used for preparing microcapsules.

Biochem./physiol. Wirkung

Magnesium stearate is the magnesium salt of stearic acid that possess lubricating properties and hence prevents ingredients from sticking to manufacturing equipment during the compression of chemical powders into solid tablets. Dry coating of drugs with magnesium stearate leads to flow improvement, flow-aid and lubrication effects, tabletability as well as non-inhibited dissolution rate.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: nwg
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves