114529

Phenolrot

ACS reagent

• Synonym(e): Phenolsulfonphthalein
• Empirische Formel (Hill-System): C₁₉H₁₄O₅S
• CAS-Nummer: 143-74-8
• Molekulargewicht: 354.38
• Beilstein: 326470
• EG-Nummer: 205-609-7
• MDL-Nummer: MFCD00003552
• UNSPSC-Code: 12171500
• PubChem Substanz-ID: 24847179
• NACRES: NA.47

Eigenschaften

• Qualität: ACS reagent
• Qualitätsniveau: 200
• Form: powder
• Klarheit der Lösung: passes test
• Methode(n): titration: suitable
• visual transition interval: 6.8-8.2, yellow to red
• Löslichkeit: water: 0.77 g/L at 100 °C
• λmax: 360 nm; 557 nm (2nd)
• ε (Extinktionskoeffizient): ≥10000 at 288-294 nm in H₂O; ≥55000 at 555-561 nm in H₂O; ≥7000 at 357-363 nm in H₂O
• Anwendung(en): diagnostic assay manufacturing; hematology; histology
• Lagertemp.: room temp
• SMILES String: Oc1ccc(cc1)C2(OS(=O)(=O)c3ccccc23)c4ccc(O)cc4
• InChI: 1S/C19H14O5S/c20-15-9-5-13(6-10-15)19(14-7-11-16(21)12-8-14)17-3-1-2-4-18(17)25(22,23)24-19/h1-12,20-21H
• InChIKey: BELBBZDIHDAJOR-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

Phenol Red is a phenolsulfonphthalein compound. It is present as a sulfonated hydroxyquinone in weakly acidic aqueous solutions. In alkaline solutions, the dye forms a hydrophilic dianion (a small, red anion that has a larger conjugated system than the yellow hydroxyquinone).

Anwendung

Phenol red is commonly used as a pH indicator in biology and medicine. It is incorporated into microbiological culture media for the identification of Escherichia coli strains. Its clinical diagnostic applications include the investigation of gastric and duodenal ulcers and the assessment of tear function in ophthalmology. Phenol red is also used as a tracer to assess the permeability of the ileal mucosal membrane and to assess bacterial leakage through root-filling materials in dentistry.
Phenol Red has been used for the preparation of phenol red gavage meal for measurement of gastric emptying in rats.

Geeignet als pH-Indikator

Biochem./physiol. Wirkung

Phenol Red is a pH indicator which changes color from yellow to red.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H315,H335
• P-Sätze: P261 - P264 - P271 - P280 - P302 + P352 - P304 + P340 + P312
• Gefahreneinstufungen: Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves