MABN666

Anti-TRIP8b Antibody, clone N212A/34

clone N212A/34, from mouse

• Synonym(e): PEX5-related protein, PEX5-like protein, Peroxin-5-related protein, TPR-containing Rab8b-interacting protein, Tetratricopeptide repeat-containing Rab8b-interacting protein, Pex5Rp, TRIP8b
• UNSPSC-Code: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: mouse
• Qualitätsniveau: 100
• Antikörperform: purified antibody
• Antikörper-Produkttyp: primary antibodies
• Klon: N212A/34, monoclonal
• Speziesreaktivität: human, rat, mouse
• Methode(n): western blot: suitable
• Isotyp: IgG1κ
• NCBI-Hinterlegungsnummer: NP_775175
• UniProt-Hinterlegungsnummer: Q925N3
• Versandbedingung: wet ice
• Posttranslationale Modifikation Target: unmodified
• Angaben zum Gen: rat ... Pex5L(286937)

Beschreibung

Allgemeine Beschreibung

Tetratricopeptide repeat-containing Rab8b-interacting protein (TRIP8b) is also called PEX5-related protein, PEX5-like protein and Peroxin-5-related protein (Pex5Rp). TRIP8b a hyperpolarization-activated cyclic nucleotide-gated (HCN) channel subunit that is involved in HCN cynclic nucleotide dependence and expression at the cell surface. TRIP8b is expressed specifically in the brain.

Spezifität

This antibody demonstrates specificity for TRIP8b containing exon 1b. It does not cross react with TRIP8b containing exons 1a, 2, or 4.

Immunogen

Recombinant protein corresponding to rat TRIP8b.

Anwendung

Research Category
Neurowissenschaft

Research Sub Category
Synapsen & Synapsenbiologie

Anti-TRIP8b Antibody, clone N212A/34 is a highly specific mouse monoclonal antibody & that targets Tetratricopeptide repeat-containing Rab8b-interacting protein & has been tested in western blotting.

Western Blotting Analysis: 0.5 μg/mL of this antibody detected TRIP8b in 10 μg of human brain tissue lysate.

Western Blotting Analysis: A representative lot detected TRIP8b in COS cell lysates transiently transfected with GFP tagged TRIP8b (exon1b) and not in COS cell lysates transiently transfected with TRIP8b (exon1a, 2, or 4) or with untagged Kv2.1 plasmid (Prof. J. Trimmer, University of California, Davis.).

Qualität

Evaluated by Western Blotting in rat brain tissue lysate.

Western Blotting Analyis: 0.5 μg/mL of this antibody detected TRIP8b in 10 μg of rat brain tissue lysate.

Zielbeschreibung

~70 kDa observed. Multiple isoforms may be observed due to alternative splicing (Lewis, A. S., et al. (2009). J Neurosci. 29(19):6250-6265.). Uncharacterized band(s) may be observed in some cell lysates.

Physikalische Form

Protein G Purified

Format: Purified

Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Lagerung und Haltbarkeit

Stable for 1 year at 2-8°C from date of receipt.

Hinweis zur Analyse

Control
Rat brain tissue lysate

Sonstige Hinweise

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable