MAB4709

Anti-Caspase 9 Antibody, clone 2-23

clone 2-23, Chemicon^®, from mouse

• Synonym(e): ICE-LAP6, Mch-6, Apaf-3
• UNSPSC-Code: 12352203
• eCl@ss: 32160702
• NACRES: NA.41
• Klon: 2-23, monoclonal
• application: IHC; IP; WB
• Speziesreaktivität: human, mouse
• Methode(n): immunohistochemistry: suitable (paraffin); immunoprecipitation (IP): suitable; western blot: suitable
• citations: 2

Eigenschaften

• Biologische Quelle: mouse
• Qualitätsniveau: 100
• Antikörperform: purified immunoglobulin
• Antikörper-Produkttyp: primary antibodies
• Klon: 2-23, monoclonal
• Speziesreaktivität: human, mouse
• Darf nicht reagieren mit: rat
• Hersteller/Markenname: Chemicon^®
• Methode(n): immunohistochemistry: suitable (paraffin); immunoprecipitation (IP): suitable; western blot: suitable
• Isotyp: IgG1
• NCBI-Hinterlegungsnummer: NM_001229.2; NM_032996.1
• UniProt-Hinterlegungsnummer: P55211
• Versandbedingung: wet ice
• Posttranslationale Modifikation Target: unmodified
• Angaben zum Gen: human ... CASP9(842)

Beschreibung

Spezifität

Recognizes 46-48 kDa full-length procaspase-9, human recombinant caspase-9 and procaspase-9 from human cell lysates. Highly specific to caspase-9 and shows no cross-reaction with other caspase family members. Activation of procaspase-9 by Apaf-1 in the cytochrome c pathway requires proteolytic cleavage to generate active caspase-9. Once activated, capsase-9 initiates a caspase cascade involving the downstream executioner caspases 3, 6 and 7.

Immunogen

Recombinant human caspase-9 prodomain

Anwendung

Research Category
Apoptose & Krebs

Stoffwechsel

Research Sub Category
Kaspasen

Enzyme & Biochemie

Anti-Caspase 9 Antibody, clone 2-23 is an antibody against Caspase 9 for use in IP, WB, IH(P).

Western blot: 1:1000 Immunohistochemistry (frozen and paraffin): 1:500 - 1:1000

Optimal working dilutions must be determined by end user.

Verlinkung

Replaces: 04-443

Physikalische Form

Format: Purified

Purified immunoglobulin by protein A. Liquid in PBS, pH 7.6, with 0.1% sodium azide.

Lagerung und Haltbarkeit

Maintain refrigerated at 2-8°C in undiluted aliquots for up to 12 months.

Sonstige Hinweise

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Rechtliche Hinweise

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 2
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable