MAB4150

Anti-MRP2 Antibody, CT, clone M2 III-6

culture supernatant, clone M2 III-6, Chemicon^®

• Synonym(e): cMOAT
• UNSPSC-Code: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: mouse
• Qualitätsniveau: 300
• Antikörperform: culture supernatant
• Antikörper-Produkttyp: primary antibodies
• Klon: M2 III-6, monoclonal
• Speziesreaktivität: human
• Hersteller/Markenname: Chemicon^®
• Methode(n): immunocytochemistry: suitable; immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable; western blot: suitable
• Isotyp: IgG2a
• NCBI-Hinterlegungsnummer: NM_000392.2
• UniProt-Hinterlegungsnummer: Q92887
• Versandbedingung: wet ice
• Angaben zum Gen: human ... ABCC2(1244)

Beschreibung

Spezifität

This antibody reacts with an internal epitope of MRP2, a 190-200 kDa transmembrane protein previously known as the canalicular multi-organic anion transporter (cMOAT). MRP2 is a member of the MRP family of multidrug resistance related proteins, and MRP2 over expression has been observed in a subset of cisplatin resistant cell lines. This antibody does not cross-react with the human MDR1, MRP1, MRP3 or MRP5 gene products.

Immunogen

Bacterial fusion protein of MRP2 containing the 202-aa C-terminal end

Epitope: C-terminus

Anwendung

Research Category
Stoffwechsel

Research Sub Category
Toxikologie & Arzneimittelresistenz

Detect MRP2 using this Anti-MRP2 Antibody, C-terminus, clone M2 III-6 validated for use in WB, IC, IH, IH(P).

Western blotting: 1:20 - 1:50 with anti-mouse HRP

Immunocytochemistry: 1:20 - 1:50 on acetone fixed cytospin preparations

Immunohistochemistry: 1:20 on acetone fixed frozen tissue sections; 1:20 on formaldehyde-fixed paraffin-embedded tissues (pretreat with 0.01M citrate, pH 6.0, in dH2O at 100ºC for 5 minutes, repeated 3 times)

Optimal working dilutions must be determined by end user.

Physikalische Form

Liquid containing 0.7% BSA and 0.1% sodium azide.

Lagerung und Haltbarkeit

Maintain refrigerated at 2-8°C for up to 6 months. For long-term storage store at -20°C.

Sonstige Hinweise

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Rechtliche Hinweise

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 2