MAB3872

Anti-PPAR γ Antibody, isoform 1&2

ascites fluid, clone 1H4, Chemicon^®

• Synonym(e): PPAR gamma
• UNSPSC-Code: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: mouse
• Qualitätsniveau: 100
• Antikörperform: ascites fluid
• Antikörper-Produkttyp: primary antibodies
• Klon: 1H4, monoclonal
• Speziesreaktivität: human, mouse
• Hersteller/Markenname: Chemicon^®
• Methode(n): ELISA: suitable; immunocytochemistry: suitable; western blot: suitable
• Isotyp: IgG1
• NCBI-Hinterlegungsnummer: NM_005037.5; NM_015869.4; NM_138711.3; NM_138712.3
• UniProt-Hinterlegungsnummer: P37231
• Versandbedingung: wet ice
• Posttranslationale Modifikation Target: unmodified
• Angaben zum Gen: human ... PPARG(5468)

Beschreibung

Allgemeine Beschreibung

Peroxisome proliferator-activated receptors (PPARs) are nuclear receptors involved in lipid transport and metabolism. As such, their roles in chronic diseases such as diabetes, obesity, atherosclerosis and cancer are heavily investigated. Transcriptional activity of PPARs is regulated by fatty acid binding. Three PPAR isotypes have been identified: a, b and g. PPARg stimulates lipolysis of circulating triglycerides and the subsequent uptake of fatty acids into adipose cells. PPARs can bind to DNA only as a heterodimer with the retinoid X receptor (RXR).

Spezifität

Reacts with human PPAR gamma2. The antibody also reacts with PPAR gamma1 due to immunogen sequence homology. The immunogen shows no homology with PPAR alpha or PPAR beta.

Immunogen

Epitope: isoform 1&2

Synthetic peptide from amino acids 107-121 of human PPAR gamma2.

Anwendung

Anti-PPAR γ Antibody, isoform 1&2 is a Mouse Monoclonal Antibody for detection of PPAR gamma also known as Peroxisome Proliferator Activated Receptor γ & has been validated in ELISA, ICC & WB.

Zielbeschreibung

67 kDa

Hinweis zur Analyse

Control
THP-1 cell lysate, 3T3-L1 cell lysate or U-937 cell lysate

Sonstige Hinweise

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Rechtliche Hinweise

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable