MAB3060
Anti-Paxillin Antibody, clone 349
clone 349, Chemicon®, from mouse
Synonym(e):
Anti-AW108311, Anti-AW123232, Anti-Pax
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About This Item
UNSPSC-Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Empfohlene Produkte
Biologische Quelle
mouse
Qualitätsniveau
Antikörperform
purified immunoglobulin
Antikörper-Produkttyp
primary antibodies
Klon
349, monoclonal
Speziesreaktivität
rat, human, mouse, canine, chicken
Hersteller/Markenname
Chemicon®
Methode(n)
ELISA: suitable
immunocytochemistry: suitable
immunohistochemistry: suitable
western blot: suitable
Isotyp
IgG1
NCBI-Hinterlegungsnummer
UniProt-Hinterlegungsnummer
Versandbedingung
wet ice
Posttranslationale Modifikation Target
unmodified
Angaben zum Gen
human ... PXN(5829)
rat ... Pxn(360820)
Spezifität
Reacts strongly with two bands on Western blots of total cell lysate from chick embryo fibroblasts or rat brain. The lower molecular band is believed to be either an isoform or a degradation product of the 68 kD protein, since it is found also on SDS-PAGE of affinity-purified paxillin.
Immunogen
Affinity purified phosphotyrosine-containing proteins from Rous sarcoma virus-transformed chick embryo fibroblasts.
Anwendung
Research Category
Zelluläre Signaltransduktion
Zelluläre Signaltransduktion
Research Sub Category
Cytoskelettale Signalübertragung
Cytoskelettale Signalübertragung
Anti-Paxillin Antibody, clone 349 detects level of Paxillin & has been published & validated for use in ELISA, WB, IC, IH.
Western blot: 1:1,000-1:10,000
ELISA
Immunohistochemistry 1:900 in Placenta
Immunocytochemistry
Immunoprecipitation
Optimal working dilutions must be determined by end user.
ELISA
Immunohistochemistry 1:900 in Placenta
Immunocytochemistry
Immunoprecipitation
Optimal working dilutions must be determined by end user.
Verlinkung
Replaces: 04-581
Physikalische Form
Format: Purified
Purified immunoglobulin. Liquid in aqueous buffered solution containing 0.09% sodium azide.
Lagerung und Haltbarkeit
Maintain at -20°C in undiluted aliquots for up to 12 months after date of receipt. Avoid repeated freeze/thaw cycles.
During shipment, small volumes of product will occasionally become entrapped in the seal of the product vial. For products with volumes of 200 μL or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container′s cap.
During shipment, small volumes of product will occasionally become entrapped in the seal of the product vial. For products with volumes of 200 μL or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container′s cap.
Hinweis zur Analyse
Control
POSITIVE CONTROL:
For western blot, load 5-10 μg of whole cell lysate prepared from the human epidermoid carcinoma cell line, A431.
POSITIVE CONTROL:
For western blot, load 5-10 μg of whole cell lysate prepared from the human epidermoid carcinoma cell line, A431.
Sonstige Hinweise
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Rechtliche Hinweise
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Haftungsausschluss
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Lagerklassenschlüssel
12 - Non Combustible Liquids
WGK
WGK 1
Analysenzertifikate (COA)
Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.
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Mechanisms of Development null
Contact between human bone marrow stromal cells and B lymphocytes enhances very late antigen-4/vascular cell adhesion molecule-1-independent tyrosine phosphorylation of focal adhesion kinase, paxillin, and ERK2 in stromal cells.
L J Jarvis, J E Maguire, T W LeBien
Blood null
F N Leeuwen et al.
The Journal of cell biology, 139(3), 797-807 (1997-11-14)
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Matrix nonenzymatic glycosylation leads to altered cellular phenotype and intracellular tyrosine phosphorylation.
Hasegawa, G, et al.
The Journal of Biological Chemistry, 270, 3278-3283 (1995)
Vinculin promotes cell spreading by mechanically coupling integrins to the cytoskeleton.
R M Ezzell, W H Goldmann, N Wang, N Parashurama, N Parasharama, D E Ingber, R M Ezzell et al.
Experimental Cell Research null
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