MAB2137
Anti-Homing Receptor Antibody, clone A020
clone A020, Chemicon®, from rat
Synonym(e):
CD44s, HCAM, Pgp-1
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Alle Fotos(1)
About This Item
UNSPSC-Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Empfohlene Produkte
Biologische Quelle
rat
Qualitätsniveau
Antikörperform
purified antibody
Antikörper-Produkttyp
primary antibodies
Klon
A020, monoclonal
Speziesreaktivität
mouse, human, rat, pig, rabbit, canine, bovine
Hersteller/Markenname
Chemicon®
Methode(n)
ELISA: suitable
flow cytometry: suitable
immunocytochemistry: suitable
immunohistochemistry: suitable
western blot: suitable
Isotyp
IgG2b
NCBI-Hinterlegungsnummer
UniProt-Hinterlegungsnummer
Versandbedingung
dry ice
Posttranslationale Modifikation Target
unmodified
Angaben zum Gen
human ... CD44(960)
Spezifität
Antibody reacts with the standard CD44 isoform (CD44s) that lacks exon sequences v1-v10. Also called human CD44 (85-95 kDa) gp90{Hermes} and mouse gp85 (Pgp-1).
Immunogen
Purified human blood lymphocyte CD44
Anwendung
Research Category
Zellstruktur
Zellstruktur
Research Sub Category
Adhäsions-Proteine (CAMs – Zelladhäsionsmoleküle)
Adhäsions-Proteine (CAMs – Zelladhäsionsmoleküle)
Anti-Homing Receptor Antibody, clone A020 is an antibody against Homing Receptor for use in ELISA, FC, IC, IH & WB.
ELISA 1:2000
Flow Cytometry :1:1000
Immunofluorescence 1:200
Immunohistostaining of paraffin embedded tissues. 1:250; antigen retrieval is usually not needed.
Immunoprecipitation 1:200
Western blotting: non-reduced conditions only; 90kDa band is detected; blocking PBS/5% milk protein, primary antibody dilution 1:1000 o/n incubation.
Optimal working dilutions must be determined by end user.
Flow Cytometry :1:1000
Immunofluorescence 1:200
Immunohistostaining of paraffin embedded tissues. 1:250; antigen retrieval is usually not needed.
Immunoprecipitation 1:200
Western blotting: non-reduced conditions only; 90kDa band is detected; blocking PBS/5% milk protein, primary antibody dilution 1:1000 o/n incubation.
Optimal working dilutions must be determined by end user.
Zielbeschreibung
90 kDa
Physikalische Form
Protein A purified
Format: Purified
Liquid in 10 mM sodium phosphate, pH 7.5 with 150 mM NaCl and 0.01% sodium azide.
Lagerung und Haltbarkeit
Maintain for 1 year at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Hinweis zur Analyse
Control
Cells of epithelium and highly expressed by carcinomas
Cells of epithelium and highly expressed by carcinomas
Sonstige Hinweise
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Rechtliche Hinweise
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Haftungsausschluss
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Lagerklassenschlüssel
12 - Non Combustible Liquids
WGK
WGK 2
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
Analysenzertifikate (COA)
Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.
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M Z Gilcrease et al.
Cancer, 86(11), 2320-2326 (1999-12-11)
Recent reports have shown altered expression of CD44 in renal cell carcinomas. However, to the authors' knowledge there are no data correlating CD44 expression in renal cell carcinomas with subsequent tumor progression or recurrence, nor is there information about the
Milan Makwana et al.
The Journal of comparative neurology, 518(5), 699-721 (2009-12-25)
Generation of new axonal sprouts plays an important role in neural repair. In the current study, we examined the appearance, composition and effects of gene deletions on intrabrainstem sprouts following peripheral facial nerve axotomy. Axotomy was followed by the appearance
Mature human thymocytes migrate on laminin-5 with activation of metalloproteinase-14 and cleavage of CD44.
Vivinus-Nebot, Mylene, et al.
Journal of immunology (Baltimore, Md. : 1950), 172, 1397-1406 (2004)
Sameerah Shaheen et al.
Stem cell reviews and reports, 12(4), 492-499 (2016-05-22)
Colorectal cancers (CRCs) form a disorganized hierarchy of heterogeneous cell populations on which current chemotherapy regimens fail to exert their distinctive cytotoxicity. A small sub-population of poorly differentiated cancer stem-like cells (CSCs), also known as cancer initiating cells, may exhibit
Carmela Ricciardelli et al.
BMC cancer, 13, 476-476 (2013-10-16)
Hyaluronan (HA) an important component of the extracellular matrix, has been linked to tumor progression and drug resistance in several malignancies. However, limited data is available for ovarian cancer. This study investigated the role of hyaluronan (HA) and a potential
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