MAB2008

Anti-Integrin β3 Antibody, clone SAP

clone SAP, Chemicon^®, from mouse

• Synonym(e): CD61
• UNSPSC-Code: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: mouse
• Qualitätsniveau: 100
• Antikörperform: purified immunoglobulin
• Antikörper-Produkttyp: primary antibodies
• Klon: SAP, monoclonal
• Speziesreaktivität: human
• Hersteller/Markenname: Chemicon^®
• Methode(n): immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable; western blot: suitable
• Isotyp: IgG1κ
• NCBI-Hinterlegungsnummer: NM_000212.2
• UniProt-Hinterlegungsnummer: P05106
• Versandbedingung: wet ice
• Posttranslationale Modifikation Target: unmodified
• Angaben zum Gen: human ... ITGB3(3690)

Beschreibung

Spezifität

Monoclonal antibody MAB2008 is specific for the beta-3 subunit of the vitronectin receptor (VNR)J, which is expressed on endothelial cells, platelets, melanoma, and glioma cells. The antibody is of high affinity.

Immunogen

Membranes of freshly isolated human platelets.

Anwendung

Detect Integrin β3 using this Anti-Integrin β3 Antibody, clone SAP validated for use in WB, IH, IH(P).

Immunohistochemistry (frozen and fixed tissue sections) including paraffin embedded sections. {See Van Belle et al 1999, original paper detailing the use in human, paraffin tissues}

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=10333228.

Western blot: recognizes ~115kDa band in reduced

Optimal working dilutions must be determined by end user.

Physikalische Form

Format: Purified

Purified immunoglobulin. Liquid at 1 mg/mL in 0.02M phosphate buffer, 0.25M sodium chloride, pH 7.6, containing 0.1% sodium azide as a preservative.

Rechtliche Hinweise

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Sicherheitshinweise

• Lagerklassenschlüssel: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable