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MAB1576

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Anti-Muscarinic Acetylcholine Receptor m4 Antibody, clone 17F10.2

purified antibody, clone 17F10.2, Chemicon®

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About This Item

UNSPSC-Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

Biologische Quelle

mouse

Qualitätsniveau

Antikörperform

purified antibody

Antikörper-Produkttyp

primary antibodies

Klon

17F10.2, monoclonal

Speziesreaktivität

mouse, monkey, rat

Hersteller/Markenname

Chemicon®

Methode(n)

immunocytochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable

Isotyp

IgG1

NCBI-Hinterlegungsnummer

UniProt-Hinterlegungsnummer

Versandbedingung

wet ice

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

mouse ... Chrm4(12672)
rat ... Chrm4(25111)
rhesus monkey ... Chrm4(574195)

Spezifität

m4 muscarinic acetylcholine receptor. No reactivity with the other subtypes.

Immunogen

m4 receptor i3 loop (human), fused to GST

Anwendung

Research Category
Neurowissenschaft
Research Sub Category
Neurotransmitter & Rezeptoren
Immunohistochemistry (rat and monkey)

Western blot (rat, mouse, human): ECL 4-10 μg/mL

Immunoprecipitation (rat)

Optimal working dilutions must be determined by the end user.
This Anti-Muscarinic Acetylcholine Receptor m4 Antibody, clone 17F10.2 is validated for use in IC, IP, WB for the detection of Muscarinic Acetylcholine Receptor m4.

Physikalische Form

Liquid in 0.02M Phosphate buffer, 0.25 M NaCl, pH=7.6 with 0.1% sodium azide.

Lagerung und Haltbarkeit

Maintain at 2-8°C in undiluted aliquots for up to 6 months.

Sonstige Hinweise

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Rechtliche Hinweise

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 2

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Die Dokumentenbibliothek aufrufen

Lack of specificity of commercially available antisera: better specifications needed.
Pradidarcheep, W; Labruyere, WT; Dabhoiwala, NF; Lamers, WH
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society null
Taketsugu Hayashi et al.
Cell reports, 30(13), 4433-4444 (2020-04-03)
The ability to infer others' mental states is essential to social interactions. This ability, critically evaluated by testing whether one attributes false beliefs (FBs) to others, has been considered to be uniquely hominid and to accompany the activation of a
Decreased expression and impaired function of muscarinic acetylcholine receptors in the rat hippocampus following transient forebrain ischemia.
Guangming Zhang, Liang Zhang, Richard Logan, Benjamin P Jung, Darren Yuen, Jee Ching Hsu et al.
Neurobiology of Disease null
Rab11a and myosin Vb regulate recycling of the M4 muscarinic acetylcholine receptor.
Volpicelli, Laura A, et al.
The Journal of Neuroscience, 22, 9776-9784 (2002)
Keita Harada et al.
Journal of pharmacological sciences, 117(4), 253-264 (2011-11-19)
The muscarinic receptor is known to be involved in the acetylcholine (ACh)-induced secretion of catecholamines in the adrenal medullary (AM) cells of various mammals. The muscarinic receptor subtype involved and its physiological role, however, have not been elucidated yet. Thus

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