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MAB1056

Sigma-Aldrich

Anti-Neutrophil Elastase Antibody, clone AHN-10

ascites fluid, clone AHN-10, Chemicon®

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About This Item

UNSPSC-Code:
12352203
eCl@ss:
32160702

Biologische Quelle

mouse

Antikörperform

ascites fluid

Antikörper-Produkttyp

primary antibodies

Klon

AHN-10, monoclonal

Speziesreaktivität

human

Hersteller/Markenname

Chemicon®

Methode(n)

immunocytochemistry: suitable
immunoprecipitation (IP): suitable
radioimmunoassay: suitable

Isotyp

IgG1

NCBI-Hinterlegungsnummer

NM_001972.2

UniProt-Hinterlegungsnummer

P08246

Versandbedingung

dry ice

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

human ... SERP1(27230)

Spezifität

Reacts specifically with human neutrophil elastase and not with the 3 homologous neutrophil neutral serine proteases, cathepsin G, esterase N and proteinase 3. Inhibits the elastinolytic activity of elastase. Elastase is felt to play an important role in a number of disease states.

Anwendung

Research Category
Entzündung & Immunologie
Research Sub Category
Entzündungs- & Autoimmunmechanismen
Anti-Neutrophil Elastase Antibody, clone AHN-10 detects level of Neutrophil Elastase & has been published & validated for use in IP, RIA & IC.
Immunoprecipitation

Immunocytochemistry

RIA

Optimal working dilutions must be determined by end user.

Lagerung und Haltbarkeit

Maintain in convenient aliquots at -20°C or colder for up to 12 months. Avoid thawing and refreezing.

Rechtliche Hinweise

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 1

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Die Dokumentenbibliothek aufrufen

M Brittany Johnson et al.
Cellular microbiology, 17(5), 648-665 (2014-10-28)
During gonorrhoeal infection, there is a heterogeneous population of Neisseria gonorrhoeae (Gc) varied in their expression of opacity-associated (Opa) proteins. While Opa proteins are important for bacterial attachment and invasion of epithelial cells, Opa+ Gc has a survival defect after
Julia Mayerle et al.
Gastroenterology, 129(4), 1251-1267 (2005-10-19)
Cadherins play an important role in cell-cell contact formation at adherens junctions. During the course of acute pancreatitis, adherens junctions are known to dissociate-a requirement for the interstitial accumulation of fluid and inflammatory cells-but the underlying mechanism is unknown. Acute
The eicosanoid response to high dose UVR exposure of individuals prone and resistant to sunburn.
Anna Nicolaou,Mojgan Masoodi,Karl Gledhill,Ann Katarina Haylett,Anthony John Thody et al.
Photochemical & Photobiological Sciences : Official Journal of the European Photochemistry Association and the European Society for Photobiology null
Severely photosensitive psoriasis: a phenotypically defined patient subset.
Kirsty J Rutter,Rachel E B Watson,Lindsey F Cotterell,Thomas Brenn et al.
The Journal of Investigative Dermatology null
K M Skubitz et al.
Journal of leukocyte biology, 44(3), 158-165 (1988-09-01)
Neutrophil proteases are believed to play a role in the pathogenesis of a variety of human diseases. While many studies of proteases in models of disease have focused on elastase, neutrophils contain several proteases some of which share a high

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