GF171

Endostatin Protein, Human Recombinant

The Endostatin protein is a naturally occurring 20 kDa polypeptide derived from the C-terminal portion of type XVIII collagen.

• Synonym(e): Collagen Type XVIII, Collagen alpha-1 (XVIII)
• UNSPSC-Code: 12352202
• eCl@ss: 32160405
• NACRES: NA.75

Eigenschaften

• Rekombinant: expressed in E. coli
• Qualitätsniveau: 100
• Assay: >98% (SDS-PAGE and HPLC)
• Verunreinigungen: <0.1 μg/mg protein endotoxin (<1EU/μg)
• UniProt-Hinterlegungsnummer: P39060
• Versandbedingung: dry ice

Beschreibung

Allgemeine Beschreibung

Endostatin is a naturally occurring 20 kDa polypeptide derived from the C-terminal portion of type XVIII collagen. It functions as an anti-angiogenic cytokine that is expressed in various organs with the highest levels in liver, lung and kidney. Endostatin inhibits angiogenesis by blocking the pro-angiogenic activities of VEGF and FGF-basic. Recombinant human Endostatin is a 20.2 kDa protein consisting 184 amino acid residues.

Product Source: E. coli.

Spezifität

Cross Reactivty
None

Anwendung

Research Category
Stammzellforschung

Research Sub Category
Wachstumsfaktoren & -rezeptoren

Qualität

Bioactivity assay: Measured by its ability to inhibit HUVEC migration.

Physikalische Form

Product is filtered through a 0.2 micron filter before lyophilization.

Lagerung und Haltbarkeit

Store at -20°C for up to 6 months from date of receipt.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 1