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EZRL

Millipore

Rat Leptin ELISA Kit

measures and quantifies Leptin levels in 10 μL plasma or serum

Synonym(e):

Leptin, Obesity Factor

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About This Item

UNSPSC-Code:
12161503
eCl@ss:
32161000
NACRES:
NA.32

product name

Rat Leptin ELISA, This Rat Leptin ELISA is used to measure & quantify Leptin levels in Metabolism & Endocrine research.

Qualitätsniveau

Speziesreaktivität

rat

Verpackung

kit of 1 × 96 wells

Parameter

10 μL sample volume (4hr assay)

assay range

accuracy: 102-122%
linearity: 87-100%
sensitivity: 0.04 ng/mL

Methode(n)

ELISA: suitable

Aufnahme

sample type plasma (K2 EDTA)
sample type serum

UniProt-Hinterlegungsnummer

Anwendung(en)

research use

Nachweisverfahren

colorimetric (450nm/590nm)

Versandbedingung

wet ice

Lagertemp.

2-8°C

Allgemeine Beschreibung

Leptin is an adipokine secreted by the adipose tissue. It is also found in the primary and secondary lymphoid organs. Leptin has a 3D structure made up of four α-helix bundle motifs. It participates in regulating neuroendocrine function and energy homeostasis. Leptin also participates in physiological processes such as reproduction, angiogenesis, and hemopoiesis. Rat Leptin enzyme-linked immunosorbent assay (ELISA) kit is used for the non-radioactive quantification of leptin in rat sera. Plasma samples may also be used but application to samples of other biological fluids may need validation by the user.

Anwendung

Rat Leptin ELISA kit has been used in the determination of leptin from rat serum and plasma samples.

Piktogramme

CorrosionExclamation mark

Signalwort

Warning

H-Sätze

Gefahreneinstufungen

Met. Corr. 1 - Skin Sens. 1

Lagerklassenschlüssel

8A - Combustible corrosive hazardous materials


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Beneficial metabolic effects of the Malaysian herb Labisia pumila var. alata in a rat model of polycystic ovary syndrome.
L Manner?s,M Fazliana,W M Wan Nazaimoon,M Lonn,H F Gu,C G Ostenson,E Stener-Victorin
Journal of Ethnopharmacology null
Giuseppe Matarese et al.
Journal of immunology (Baltimore, Md. : 1950), 174(6), 3137-3142 (2005-03-08)
Leptin is an adipokine which conveys information on energy availability. In humans, leptin influences energy homeostasis and regulates neuroendocrine function primarily in states of energy deficiency. As a cytokine, leptin also affects thymic homeostasis and, similar to other proinflammatory cytokines
Staci D Bilbo et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 24(6), 2104-2115 (2010-02-04)
Obesity is well characterized as a systemic inflammatory condition, and is also associated with cognitive disruption, suggesting a link between the two. We assessed whether peripheral inflammation in maternal obesity may be transferred to the offspring brain, in particular, the
Effects of high-fat high-sucrose feeding, energy restriction, and trans-10,cis-12 conjugated linoleic acid on visfatin and apelin in hamsters.
Arrate Lasa,Itziar Churruca,Edurne Simon,Maria Teresa Macarulla et al.
Journal of the American College of Nutrition null
Bérengère Coupé et al.
PloS one, 7(1), e30616-e30616 (2012-02-01)
Intrauterine growth restriction (IUGR) is closely linked with metabolic diseases, appetite disorders and obesity at adulthood. Leptin, a major adipokine secreted by adipose tissue, circulates in direct proportion to body fat stores, enters the brain and regulates food intake and

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